(Q50533155)

14 March 2018

title

The effects of amino acid replacements of glycine 121 on transmembrane helix 3 of rhodopsin. (English)

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14 March 2018

main subject

transmembrane protein

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author name string

M Han

1

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14 March 2018

S W Lin

2

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14 March 2018

S O Smith

3

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14 March 2018

T P Sakmar

4

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14 March 2018

language of work or name

English

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publication date

1 December 1996

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14 March 2018

Journal of Biological Chemistry

published in

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14 March 2018

volume

271

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14 March 2018

issue

50

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14 March 2018

page(s)

32330-32336

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14 March 2018

Structure and function of G protein-coupled receptors

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Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin

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Effect of carboxylic acid side chains on the absorption maximum of visual pigments

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Deprotonation of the Schiff base of rhodopsin is obligate in the activation of the G protein.

21 January 2018

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21 January 2018

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Rhodopsin mutants that bind but fail to activate transducin

21 January 2018

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Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin

21 January 2018

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Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.

21 January 2018

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Nature of the primary photochemical events in rhodopsin and bacteriorhodopsin

21 January 2018

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Localization of the retinal protonated Schiff base counterion in rhodopsin

21 January 2018

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NMR constraints on the location of the retinal chromophore in rhodopsin and bathorhodopsin

21 January 2018

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High-resolution structural studies of the retinal--Glu113 interaction in rhodopsin

21 January 2018

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Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

21 January 2018

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The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa

21 January 2018

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Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons

21 January 2018

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21 January 2018

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Expression of a synthetic bovine rhodopsin gene in monkey kidney cells

21 January 2018

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Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa

21 January 2018

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21 January 2018

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Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

21 January 2018

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What makes red visual pigments red? A resonance Raman microprobe study of retinal chromophore structure in iodopsin

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Structure and function of rhodopsins from solid state NMR and resonance Raman spectroscopy of isotopic retinal derivatives

21 January 2018

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Double point charge model for visual pigments; evidence from dihydrorhodopsins

21 January 2018

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Two-photon spectroscopy of locked-11-cis-rhodopsin: evidence for a protonated Schiff base in a neutral protein binding site

21 January 2018

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Activating mutations of rhodopsin and other G protein-coupled receptors

21 January 2018

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Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

21 January 2018

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Glycine and beta-branched residues support and modulate peptide helicity in membrane environments

21 January 2018

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Role of transmembrane domain interactions in the assembly of class II MHC molecules

21 January 2018

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Sequence specificity in the dimerization of transmembrane alpha-helices

21 January 2018

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Determination of helix-helix interactions in membranes by rotational resonance NMR

21 January 2018

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Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method

21 January 2018

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A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice.

21 January 2018

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Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin

21 January 2018

1 reference

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Projection structure of rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.50.32330

Structural invariants in protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.50.32330

21 January 2018

Identifiers

DOI

10.1074/JBC.271.50.32330

1 reference

14 March 2018

1 reference

14 March 2018