(Q50603264)

16 March 2018

title

A Pyk2-Vav1 complex is recruited to beta3-adhesion sites to initiate Rho activation. (English)

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16 March 2018

author name string

Chunlei Gao

series ordinal

1

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16 March 2018

Scott D Blystone

series ordinal

2

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16 March 2018

language of work or name

English

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publication date

28 April 2009

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16 March 2018

published in

Biochemical Journal

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16 March 2018

volume

420

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16 March 2018

issue

1

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16 March 2018

page(s)

49-56

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16 March 2018

Tyrosine phosphorylation of beta3 integrin provides a binding site for Pyk2.

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav family proteins couple to diverse cell surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav-family proteins in T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Structural determinants for the biological activity of Vav proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

RAFTK/Pyk2-mediated cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Src family kinases mediate neutrophil adhesion to adherent platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Requirement of integrin beta3 tyrosine 747 for beta3 tyrosine phosphorylation and regulation of alphavbeta3 avidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090037

21 January 2018

Identifiers

DOI

10.1042/BJ20090037

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16 March 2018

PubMed ID

19207108

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16 March 2018