(Q50634713)

English

Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa.

scientific article published in June 2011

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21470189%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21470189%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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apoptotic process

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5

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27 January 2020

author name string

Adam J Koppers

1

1 reference

Europe PubMed Central

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27 January 2020

Lisa A Mitchell

2

1 reference

Europe PubMed Central

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27 January 2020

Ping Wang

3

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21470189%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Minjie Lin

4

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27 January 2020

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publication date

1 June 2011

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27 January 2020

number of pages

12

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Biochemical Journal

1 reference

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27 January 2020

436

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27 January 2020

3

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27 January 2020

687-698

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27 January 2020

On the possible origins of DNA damage in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Mechanisms of toxic damage to spermatogenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Enrichment of non-apoptotic human spermatozoa after cryopreservation by immunomagnetic cell sorting.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Early apoptotic changes in human spermatozoa and their relationships with conventional semen parameters and sperm DNA fragmentation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

A novel approach for the selection of human sperm using annexin V-binding and flow cytometry

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Cryopreservation and thawing is associated with varying extent of activation of apoptotic machinery in subsets of ejaculated human spermatozoa

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Caspase-3 activation and phosphatidylserine membrane translocation in human spermatozoa: is there a relationship?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Prolactin exerts a prosurvival effect on human spermatozoa via mechanisms that involve the stimulation of Akt phosphorylation and suppression of caspase activation and capacitation.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Somatic cell apoptosis markers and pathways in human ejaculated sperm: potential utility as indicators of sperm quality

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Endonuclease G is required for early embryogenesis and normal apoptosis in mice

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Bisperoxovanadium compounds are potent PTEN inhibitors.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Identification of ras and its downstream signaling elements and their potential role in hamster sperm motility.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Inhibitors of phosphoinositide 3-kinase, LY294002 and wortmannin, affect sperm capacitation and associated phosphorylation of proteins differently: Ca2+-dependent divergences

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Intracellular signal transduction pathways in the regulation of fowl sperm motility: evidence for the involvement of phosphatidylinositol 3-kinase (PI3-K) cascade

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Phosphatidylinositol 3-kinase pathway regulates sperm viability but not capacitation on boar spermatozoa

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Constitutive neutrophil apoptosis: mechanisms and regulation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Relationship between caspase activity and apoptotic markers in human sperm in response to hydrogen peroxide and progesterone

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Staining of human sperm with fluorochrome-labeled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameters

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Selection of nonapoptotic spermatozoa as a new tool for enhancing assisted reproduction outcomes: an in vitro model

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

A novel nuclease activity that is activated by Ca(2+) chelated to EGTA

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Integrity of mitochondrial membrane potential reflects human sperm quality

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Can programmed cell death be induced in post-ejaculatory bull and stallion spermatozoa?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Assessment of fresh and frozen-thawed boar semen using an Annexin-V assay: a new method of evaluating sperm membrane integrity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Whole-body heat exposure induces membrane changes in spermatozoa from the cauda epididymidis of laboratory mice

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

The TUNEL assay consistently underestimates DNA damage in human spermatozoa and is influenced by DNA compaction and cell vitality: development of an improved methodology

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

Seeds of concern

1 reference

https://api.crossref.org/works/10.1042%2FBJ20110114

21 January 2018

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