(Q50636616)

17 March 2018

title

Lymphocyte fate specification as a deterministic but highly plastic process. (English)

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17 March 2018

author name string

Steven L Reiner

series ordinal

1

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17 March 2018

William C Adams

series ordinal

2

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17 March 2018

publication date

5 September 2014

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17 March 2018

Nature Reviews Immunology

published in

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17 March 2018

volume

14

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17 March 2018

issue

10

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17 March 2018

page(s)

699-704

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17 March 2018

Environmental cues dictate the fate of individual CD8+ T cells responding to infection

cites work

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Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

21 January 2018

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A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.

21 January 2018

1 reference

One naive T cell, multiple fates in CD8+ T cell differentiation.

21 January 2018

1 reference

Heterogeneous differentiation patterns of individual CD8+ T cells.

21 January 2018

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Disparate individual fates compose robust CD8+ T cell immunity

21 January 2018

1 reference

Helper T cell differentiation is controlled by the cell cycle

21 January 2018

1 reference

B cell differentiation and isotype switching is related to division cycle number

21 January 2018

1 reference

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

21 January 2018

1 reference

Intraclonal generation of antibody mutants in germinal centres

21 January 2018

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Activation-induced B cell fates are selected by intracellular stochastic competition.

21 January 2018

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Cutting edge: Asymmetric memory T cell division in response to rechallenge

21 January 2018

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Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses.

21 January 2018

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Asymmetric B cell division in the germinal center reaction.

21 January 2018

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CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells

21 January 2018

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Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

21 January 2018

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Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

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T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology

21 January 2018

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Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms

21 January 2018

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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

21 January 2018

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Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection

21 January 2018

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Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity.

21 January 2018

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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

21 January 2018

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

21 January 2018

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Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

21 January 2018

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Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

21 January 2018

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

21 January 2018

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Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation.

21 January 2018

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Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.

21 January 2018

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Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics

21 January 2018

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Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues.

21 January 2018

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Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

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How B cells capture, process and present antigens: a crucial role for cell polarity

21 January 2018

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Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like responsein vivo

21 January 2018

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Asymmetric Segregation of Polarized Antigen on B Cell Division Shapes Presentation Capacity

21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/NRI3734

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17 March 2018

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17 March 2018