(Q50644999)

17 March 2018

title

Characterization of hepatobiliary transport systems of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035. (English)

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17 March 2018

author name string

Minoru Tsuda-Tsukimoto

1

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17 March 2018

Tomoji Maeda

2

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17 March 2018

Takashi Iwanaga

3

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17 March 2018

Toshiyuki Kume

4

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17 March 2018

Ikumi Tamai

5

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17 March 2018

publication date

13 September 2006

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17 March 2018

published in

Pharmaceutical Research

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17 March 2018

volume

23

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17 March 2018

issue

11

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17 March 2018

page(s)

2646-2656

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17 March 2018

A pharmacokinetic analysis program (multi) for microcomputer

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9102-6

The complexities of hepatic drug transport: current knowledge and emerging concepts.

21 January 2018

1 reference

12 December 2020

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

1 reference

12 December 2020

Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

1 reference

12 December 2020

Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)

1 reference

12 December 2020

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

1 reference

12 December 2020

The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

1 reference

12 December 2020

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist

1 reference

12 December 2020

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis

1 reference

12 December 2020

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

1 reference

12 December 2020

Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C.

1 reference

12 December 2020

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

1 reference

12 December 2020

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

1 reference

12 December 2020

Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

1 reference

12 December 2020

The roles of transporters and enzymes in hepatic drug processing

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12 December 2020

Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

1 reference

12 December 2020

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

1 reference

12 December 2020

Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity

1 reference

12 December 2020

Transport of ochratoxin A by renal multispecific organic anion transporter 1

1 reference

12 December 2020

The SLC22 drug transporter family

1 reference

12 December 2020

Role of human liver cytochrome P450 2C9 in the metabolism of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035.

1 reference

12 December 2020

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).

1 reference

12 December 2020

Pharmacokinetics and metabolism of TR-14035, a novel antagonist of a4ss1/a4ss7 integrin mediated cell adhesion, in rat and dog.

1 reference

12 December 2020

Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

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12 December 2020

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

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12 December 2020

Criteria of Viability of Isolated Liver Cells

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12 December 2020

Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin

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12 December 2020

ABCG2 -- a transporter for all seasons

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12 December 2020

Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay

1 reference

12 December 2020

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1 reference

12 December 2020

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

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12 December 2020

Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918.

1 reference

12 December 2020

Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

1 reference

12 December 2020

Transport systems of isolated hepatocytes. Studies on the transport of biliary compounds

1 reference

12 December 2020

Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

1 reference

12 December 2020

10.1007/S11095-006-9102-6

Identifiers

DOI

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17 March 2018

PubMed ID

16969695

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17 March 2018