(Q50645066)

17 March 2018

title

Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain. (English)

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17 March 2018

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Shailaja Sopory

1

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17 March 2018

Sylvia M Nelsen

2

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17 March 2018

Catherine Degnin

3

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17 March 2018

Crispin Wong

4

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17 March 2018

Jan L Christian

5

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17 March 2018

language of work or name

English

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publication date

11 September 2006

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17 March 2018

Journal of Biological Chemistry

published in

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17 March 2018

volume

281

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issue

45

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17 March 2018

page(s)

34021-34031

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17 March 2018

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

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Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7 heterodimer

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BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

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Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

21 January 2018

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Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4.

21 January 2018

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Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity.

21 January 2018

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21 January 2018

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Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus

21 January 2018

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Nodal stability determines signaling range.

21 January 2018

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Requirement for activin A and transforming growth factor--beta 1 pro-regions in homodimer assembly.

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Processed Vg1 protein is an axial mesoderm inducer in Xenopus

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Latent TGF-beta binding proteins

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Emilin1 links TGF-beta maturation to blood pressure homeostasis

21 January 2018

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The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix

21 January 2018

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Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1

21 January 2018

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Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9. Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep

21 January 2018

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Dominant negative mutants of transforming growth factor-beta 1 inhibit the secretion of different transforming growth factor-beta isoforms

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605330200

1 reference

17 March 2018

1 reference

17 March 2018