(Q50660457)

17 March 2018

title

Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation. (English)

1 reference

17 March 2018

author name string

David Fernandez

1

1 reference

17 March 2018

Azad Ghanta

2

1 reference

17 March 2018

Krista I Kinard

3

1 reference

17 March 2018

Michael C Sanguinetti

4

1 reference

17 March 2018

language of work or name

English

0 references

publication date

23 June 2005

1 reference

17 March 2018

published in

Journal of Physiology

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17 March 2018

volume

567

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17 March 2018

issue

Pt 3

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17 March 2018

page(s)

737-755

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17 March 2018

Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating

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Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel

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Gating currents associated with intramembrane charge displacement in HERG potassium channels

25 August 2018

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Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation

25 August 2018

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Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes

25 August 2018

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The principle of gating charge movement in a voltage-dependent K+ channel

25 August 2018

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X-ray structure of a voltage-dependent K+ channel

25 August 2018

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Structural basis of two-stage voltage-dependent activation in K+ channels

25 August 2018

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Structural and functional role of the extracellular s5-p linker in the HERG potassium channel

25 August 2018

1 reference

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Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels

25 August 2018

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Molecular and cellular mechanisms of cardiac arrhythmias

25 August 2018

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Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3.

25 August 2018

1 reference

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A structural basis for drug-induced long QT syndrome

25 August 2018

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Altered gating of HERG potassium channels by cobalt and lanthanum

25 August 2018

1 reference

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Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à-Go-Go potassium channels

25 August 2018

1 reference

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Voltage-dependent structural interactions in the Shaker K(+) channel

25 August 2018

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pH-dependent inhibition of voltage-gated H(+) currents in rat alveolar epithelial cells by Zn(2+) and other divalent cations

25 August 2018

1 reference

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Enhancement of HERG K+ currents by Cd2+ destabilization of the inactivated state

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Proton and zinc effects on HERG currents

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Divalent cation effects on the Shaker K channel suggest a pentapeptide sequence as determinant of functional surface charge density

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Effects of divalent cations on the E-4031-sensitive repolarization current, I(Kr), in rabbit ventricular myocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Surface Charges of K channels. Effects of strontium on five cloned channels expressed in Xenopus oocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Fast inactivation causes rectification of the IKr channel

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

The inward rectification mechanism of the HERG cardiac potassium channel

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

A family of potassium channel genes related to eag in Drosophila and mammals

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Electrostatic interactions of S4 voltage sensor in shaker K+ channel

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Block of squid axon K channels by internally and externally applied barium ions

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Divalent cations and the activation kinetics of potassium channels in squid giant axons

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

The electrostatic properties of membranes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

The role of divalent cations in potassium channels

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

External calcium ions are required for potassium channel gating in squid neurons.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Delayed rectifier outward K+ current is composed of two currents in guinea pig atrial cells.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Modulation of the delayed rectifier, IK, by cadmium in cat ventricular myocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Electrophysiological recording from Xenopus oocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474238

Coordination geometries of selected transition metal ions (Co2+, Ni2+, Cu2+, Zn2+, Cd2+, and Hg2+) in metalloproteins

25 August 2018

1 reference

12 December 2020

Blockade of the delayed rectifier K+ currents, IKr, in rabbit sinoatrial node cells by external divalent cations

1 reference

12 December 2020

A novel extracellular calcium sensing mechanism in voltage-gated potassium ion channels

1 reference

12 December 2020

Voltage- and time-dependent block of delayed rectifier K+ current in rabbit sino-atrial node cells by external Ca2+ and Mg2+

1 reference

12 December 2020

Effects of cadmium and nisoldipine on the delayed rectifier potassium current in guinea pig ventricular myocytes

1 reference

12 December 2020

10.1113/JPHYSIOL.2005.089094

Identifiers

DOI

1 reference

17 March 2018

release_kpbfmhuiq5cznifpxcmmnaucn4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kpbfmhuiq5cznifpxcmmnaucn4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1474238

0 references

1 reference

17 March 2018