(Q50667468)

17 March 2018

title

Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein. (English)

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17 March 2018

main subject

transmembrane protein

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Yoshinori Kashiwayama

1

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17 March 2018

Kota Asahina

2

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17 March 2018

Masashi Morita

3

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17 March 2018

Tsuneo Imanaka

4

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17 March 2018

language of work or name

English

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publication date

30 August 2007

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17 March 2018

Journal of Biological Chemistry

published in

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17 March 2018

volume

282

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17 March 2018

issue

46

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17 March 2018

page(s)

33831-33844

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17 March 2018

Cellular and molecular aspects of Zellweger syndrome and other peroxisome biogenesis disorders

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Peroxisome biogenesis and peroxisome biogenesis disorders

21 January 2018

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Biogenesis of peroxisomes

21 January 2018

1 reference

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A conserved tripeptide sorts proteins to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting.

21 January 2018

1 reference

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The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells--the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Protein import into peroxisomes and biogenesis of the organelle

21 January 2018

1 reference

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Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins

21 January 2018

1 reference

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Defective peroxisome membrane synthesis due to mutations in human PEX3 causes Zellweger syndrome, complementation group G

21 January 2018

1 reference

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Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly

21 January 2018

1 reference

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Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

The peroxin Pex19p interacts with multiple, integral membrane proteins at the peroxisomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Role of Pex19p in the targeting of PMP70 to peroxisome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Function of the PEX19-binding site of human adrenoleukodystrophy protein as targeting motif in man and yeast. PMP targeting is evolutionarily conserved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

An internal region of the peroxisomal membrane protein PMP47 is essential for sorting to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

The sorting sequence of the peroxisomal integral membrane protein PMP47 is contained within a short hydrophilic loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

A stretch of positively charged amino acids at the N terminus of Hansenula polymorpha Pex3p is involved in incorporation of the protein into the peroxisomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Topogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Multiple distinct targeting signals in integral peroxisomal membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Characterization of the 70-kDa peroxisomal membrane protein, an ATP binding cassette transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Insertion of the 70-kDa peroxisomal membrane protein into peroxisomal membranes in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Multiple targeting modules on peroxisomal proteins are not redundant: discrete functions of targeting signals within Pmp47 and Pex8p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

M-LP, Mpv17-like protein, has a peroxisomal membrane targeting signal comprising a transmembrane domain and a positively charged loop and up-regulates expression of the manganese superoxide dismutase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Targeting signals in peroxisomal membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

Potential role for Pex19p in assembly of PTS-receptor docking complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703369200

21 January 2018

Identifiers

DOI

10.1074/JBC.M703369200

1 reference

17 March 2018

1 reference

17 March 2018