(Q50678899)

17 March 2018

title

Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action. (English)

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17 March 2018

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Keertik Fulzele

1

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17 March 2018

Douglas J DiGirolamo

2

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17 March 2018

Zhongyu Liu

3

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17 March 2018

Jie Xu

4

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17 March 2018

Joseph L Messina

5

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17 March 2018

Thomas L Clemens

6

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17 March 2018

language of work or name

English

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publication date

6 June 2007

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17 March 2018

Journal of Biological Chemistry

published in

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17 March 2018

volume

282

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17 March 2018

issue

35

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17 March 2018

page(s)

25649-25658

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17 March 2018

Distinct and overlapping functions of insulin and IGF-I receptors

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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Expression, characterization, and crystallization of the catalytic core of the human insulin receptor protein-tyrosine kinase domain

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Cell signaling by receptor tyrosine kinases

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Critical nodes in signalling pathways: insights into insulin action

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Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

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Modeling error and stability of endothelial cytoskeletal membrane parameters based on modeling transendothelial impedance as resistor and capacitor in series.

21 January 2018

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Bone formation is impaired in a model of type 1 diabetes.

21 January 2018

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The effects of local insulin delivery on diabetic fracture healing

21 January 2018

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Comparison of TGF-beta/BMP pathways signaled by demineralized bone powder and BMP-2 in human dermal fibroblasts

21 January 2018

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

21 January 2018

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The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

21 January 2018

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Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus

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Molecular and cellular aspects of the insulin-like growth factor I receptor

21 January 2018

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Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.

21 January 2018

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Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

21 January 2018

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Demonstration of insulin receptors and modulation of alkaline phosphatase activity by insulin in rat osteoblastic cells

21 January 2018

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Multiple Hormonal Mechanisms for the Control of Collagen Synthesis in an Osteoblast-Like Cell Line, MMB-1*

21 January 2018

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Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain

21 January 2018

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Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.

21 January 2018

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Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells

21 January 2018

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Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

21 January 2018

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Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes

21 January 2018

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Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

21 January 2018

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The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

21 January 2018

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Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.

21 January 2018

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Insulin stimulates glucose metabolism via the pentose phosphate pathway in Drosophila Kc cells

21 January 2018

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The Drosophila insulin receptor is required for normal growth

21 January 2018

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Normal bone density obtained in the absence of insulin receptor expression in bone.

21 January 2018

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Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

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Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA translation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M700651200

1 reference

17 March 2018

PubMed ID

17553792

1 reference

17 March 2018