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English
Overexpression of Bcl-2 or Bcl-xL prevents spiral ganglion neuron death and inhibits neurite growth.
scientific article published in February 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
title
Overexpression of Bcl-2 or Bcl-xL prevents spiral ganglion neuron death and inhibits neurite growth
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
main subject
overexpression
1 reference
based on heuristic
inferred from title
neurite
1 reference
based on heuristic
inferred from title
author
Marlan R Hansen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
author name string
Pamela C Roehm
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Ningyong Xu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Steven H Green
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
publication date
1 February 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
number of pages
10
1 reference
based on heuristic
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published in
Developmental Neurobiology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
volume
67
1 reference
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Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
page(s)
316-325
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
cites work
How cochlear implants encode speech.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
21 January 2018
The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methods for providing therapeutic agents to treat damaged spiral ganglion neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degeneration of cochlear neurons after amikacin intoxication in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 promotes regeneration of severed axons in mammalian CNS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Optic nerve crush: axonal responses in wild-type and bcl-2 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Re-establishing the regenerative potential of central nervous system axons in postnatal mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Response of spiral ganglion neurones to cochlear hair cell destruction in the guinea pig.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical application of neurotrophic factors: the potential for primary auditory neuron protection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 family members and the mitochondria in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2+/calmodulin-dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trophic support of cultured spiral ganglion neurons by depolarization exceeds and is additive with that by neurotrophins or cAMP and requires elevation of [Ca2+]i within a set range.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guiding neuronal growth cones using Ca2+ signals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cochlear Nerve Stimulation with a 3-Dimensional Penetrating Electrode Array
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 influences axonal growth rate in embryonic sensory neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced axonal growth from fetal human bcl-2 transgenic mouse dopamine neurons transplanted to the adult rat striatum.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 overexpression does not enhance in vivo axonal regeneration of retinal ganglion cells after peripheral nerve transplantation in adult mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 enhances Ca(2+) signaling to support the intrinsic regenerative capacity of CNS axons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium regulation of the neuronal growth cone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of growth cone behavior by calcium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired regeneration of bcl-2-lacking peripheral nerves
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain activity in the amikacin-damaged rat cochlea
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of calcineurin by growth cone calcium waves controls neurite extension.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic intracochlear electrical stimulation in neonatally deafened cats: effects of intensity and stimulating electrode location
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel model for rapid induction of apoptosis in spiral ganglions of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor interactions in cultures of dissociated adult acoustic ganglia: neuronotrophic effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of neurotrophins on early auditory neurones in cell culture.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NT-3 has a tropic effect on process outgrowth by postnatal auditory neurones in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 gene family in the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of chronic high-rate electrical stimulation on the cochlea and eighth nerve in the deafened guinea pig.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated expression of brain-derived neurotrophic factor protects spiral ganglion neurons from ototoxic damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Bcl-2 in a murine dopaminergic neuronal cell line leads to neurite outgrowth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial mechanisms of neural cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium and apoptosis: facts and hypotheses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strategies to preserve or regenerate spiral ganglion neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA plasmid that codes for human Bcl-2 gene preserves axotomized Clarke's nucleus neurons and reduces atrophy after spinal cord hemisection in adult rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cerebellar Purkinje cell numbers in mice overexpressing a human bcl-2 transgene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BDNF synthesis in spiral ganglion neurons is constitutive and CREB-dependent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
bcl-2 protects HL-60 cells from apoptosis by stabilizing their intracellular calcium pools
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patterns of degeneration in the human cochlear nerve
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDNEU.20346
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/DNEU.20346
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PubMed publication ID
17443790
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17443790
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17443790%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
ResearchGate publication ID
6384544
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