(Q50703486)

17 March 2018

title

Thiopurine methyltransferase activity in Spain: a study of 14,545 patients. (English)

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17 March 2018

author

Javier P Gisbert

1

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17 March 2018

author name string

Fernando Gomollón

2

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17 March 2018

Carlos Cara

3

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17 March 2018

Marta Luna

4

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17 March 2018

Yago González-Lama

5

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17 March 2018

José María Pajares

6

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17 March 2018

José Maté

7

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17 March 2018

Luis G Guijarro

8

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17 March 2018

publication date

2 March 2007

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17 March 2018

Digestive Diseases and Sciences

published in

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17 March 2018

volume

52

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17 March 2018

issue

5

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17 March 2018

page(s)

1262-1269

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17 March 2018

https://scigraph.springernature.com/pub.10.1007/s10620-006-9119-z

exact match

0 references

cites work

Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10620-006-9119-Z

Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10620-006-9119-Z

Thiopurine methyltransferase activity and myelosuppression in inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine

21 January 2018

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12 December 2020

Thiopurine S-methyltransferase activity in human erythrocytes: a new HPLC method using 6-thioguanine as substrate

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12 December 2020

Long-term results of TPMT activity monitoring in azathioprine-treated renal allograft recipients

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12 December 2020

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12 December 2020

High 6-thioguanine nucleotide levels and low thiopurine methyltransferase activity in patients with lupus erythematosus treated with azathioprine

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12 December 2020

Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease

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12 December 2020

Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: comparison with the radiochemical method

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12 December 2020

Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes

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Thiopurine methyltransferase: a review and a clinical pilot study

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Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity

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The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients

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12 December 2020

Effective maintenance of inflammatory bowel disease remission by azathioprine does not require concurrent 5-aminosalicylate therapy

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Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

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Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction

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Azathioprine myelotoxicity related to elevated 6-thioguanine nucleotides in heart transplantation

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Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations

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Balsalazide and azathiprine or 6-mercaptopurine: evidence for a potentially serious drug interaction

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Azathioprine for maintaining remission of Crohn's disease

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12 December 2020

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

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Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia

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Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

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12 December 2020

Thiopurine methyltransferase activity in a Spanish population sample: decrease of enzymatic activity in multiple sclerosis patients

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Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease

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Monitoring of azathioprine-induced immunosuppression with thiopurine methyltransferase activity in kidney transplant recipients

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A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine

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Azathioprine and methotrexate in multiple sclerosis

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Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low-dose azathioprine

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12 December 2020

Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.

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The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients

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12 December 2020

Thiopurine methyltransferase activity in a Korean population sample of children.

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12 December 2020

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

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12 December 2020

A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine

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Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

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Thiopurine methyltransferase activity in the Jewish population of Israel

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Therapeutic drug monitoring of antimetabolic cytotoxic drugs

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Human thiopurine S-methyltransferase activity in uremia and after renal transplantation

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Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

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12 December 2020

Treatment of autoimmune hepatitis

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12 December 2020

10.1007/S10620-006-9119-Z

Identifiers

DOI

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17 March 2018

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17 March 2018