(Q50710653)

18 March 2018

title

IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry. (English)

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18 March 2018

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Kris A Demali

1

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18 March 2018

April L Jue

series ordinal

2

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18 March 2018

Keith Burridge

series ordinal

3

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18 March 2018

language of work or name

English

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publication date

22 October 2006

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18 March 2018

Journal of Biological Chemistry

number of pages

8

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based on heuristic

inferred from page(s)

published in

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18 March 2018

volume

281

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18 March 2018

issue

51

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18 March 2018

page(s)

39534-39541

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18 March 2018

Type III secretion systems and bacterial flagella: insights into their function from structural similarities

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1 reference

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IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation

21 January 2018

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Characterization of the interaction partners of secreted proteins and chaperones of Shigella flexneri.

21 January 2018

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Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells

21 January 2018

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Virulence-associated genetic regions comprising 31 kilobases of the 230-kilobase plasmid in Shigella flexneri 2a.

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Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin.

21 January 2018

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rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells

21 January 2018

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Coupling membrane protrusion and cell adhesion

21 January 2018

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IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells

21 January 2018

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Abl tyrosine kinases are required for infection by Shigella flexneri

21 January 2018

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Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

21 January 2018

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

21 January 2018

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

21 January 2018

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Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

21 January 2018

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CD44 binds to the Shigella IpaB protein and participates in bacterial invasion of epithelial cells

21 January 2018

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Interaction of Ipa proteins of Shigella flexneri with alpha5beta1 integrin promotes entry of the bacteria into mammalian cells

21 January 2018

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Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization.

21 January 2018

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Spatial distribution and functional significance of activated vinculin in living cells

21 January 2018

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Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion

21 January 2018

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Characterization of invasion plasmid antigen genes (ipaBCD) from Shigella flexneri

21 January 2018

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Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.

21 January 2018

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

21 January 2018

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

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Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility

21 January 2018

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

21 January 2018

1 reference

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RhoA is required for cortical retraction and rigidity during mitotic cell rounding

21 January 2018

1 reference

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Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

21 January 2018

1 reference

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Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605939200

1 reference

18 March 2018

1 reference

18 March 2018