(Q50711106)

18 March 2018

title

Structural basis of peroxide-mediated changes in human hemoglobin: a novel oxidative pathway. (English)

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18 March 2018

author name string

Yiping Jia

1

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18 March 2018

Paul W Buehler

2

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18 March 2018

Robert A Boykins

3

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18 March 2018

Richard M Venable

4

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18 March 2018

Abdu I Alayash

5

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18 March 2018

language of work or name

English

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publication date

17 December 2006

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18 March 2018

Journal of Biological Chemistry

published in

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18 March 2018

volume

282

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18 March 2018

issue

7

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18 March 2018

page(s)

4894-4907

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18 March 2018

Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma.

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Quantification and significance of protein oxidation in biological samples

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Oxygen therapeutics: can we tame haemoglobin?

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Site-specific cross-linking of human and bovine hemoglobins differentially alters oxygen binding and redox side reactions producing rhombic heme and heme degradation

21 January 2018

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The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology

21 January 2018

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Hydrogen peroxide-mediated alteration of the heme prosthetic group of metmyoglobin to an iron chlorin product: evidence for a novel oxidative pathway

21 January 2018

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Comparative study of tyrosine radicals in hemoglobin and myoglobins treated with hydrogen peroxide

21 January 2018

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UVA-ketoprofen-induced hemoglobin radicals detected by immuno-spin trapping

21 January 2018

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Identification of free radicals on hemoglobin from its self-peroxidation using mass spectrometry and immuno-spin trapping: observation of a histidinyl radical

21 January 2018

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Immunochemical detection of hemoglobin-derived radicals formed by reaction with hydrogen peroxide: involvement of a protein-tyrosyl radical

21 January 2018

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Using anti-5,5-dimethyl-1-pyrroline N-oxide (anti-DMPO) to detect protein radicals in time and space with immuno-spin trapping

21 January 2018

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O-raffinose crosslinked hemoglobin lacks site-specific chemistry in the central cavity: structural and functional consequences of beta93Cys modification

21 January 2018

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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How to study proteins by circular dichroism

21 January 2018

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Differential susceptibilities of the prosthetic heme of hemoglobin-based red cell substitutes. Implications in the design of safer agents.

21 January 2018

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Ion trap collision-induced dissociation of human hemoglobin alpha-chain cations.

21 January 2018

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Transmutation of a heme protein

21 January 2018

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Characteristics and mechanism of formation of peroxide-induced heme to protein cross-linking in myoglobin

21 January 2018

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Methionine oxidation and aging

21 January 2018

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Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).

21 January 2018

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Oxidation of hypotaurine and cysteine sulphinic acid by peroxynitrite

21 January 2018

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Development of a peptide mapping procedure to identify and quantify methionine oxidation in recombinant human alpha1-antitrypsin.

21 January 2018

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The reactivity and oxidation pathway of cysteine 232 in recombinant human alpha 1-antitrypsin.

21 January 2018

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Oxidative modification by low levels of HOOH can transform myoglobin to an oxidase

21 January 2018

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Covalent crosslinking of the heme prosthetic group to myoglobin by H2O2: toxicological implications

21 January 2018

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Role of heme-protein covalent bonds in mammalian peroxidases. Protection of the heme by a single engineered heme-protein link in horseradish peroxidase

21 January 2018

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Oxygen carriers ("blood substitutes")--raison d'etre, chemistry, and some physiology

21 January 2018

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Oxidative mechanisms of hemoglobin-based blood substitutes

21 January 2018

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CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M609955200

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18 March 2018

PubMed ID

17178725

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18 March 2018