(Q50746326)

18 March 2018

title

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP. (English)

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18 March 2018

main subject

NAADP

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ChEBI release 2020-05-28

5

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18 March 2018

author name string

Dev Churamani

1

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18 March 2018

Robert Hooper

2

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18 March 2018

Taufiq Rahman

3

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18 March 2018

Eugen Brailoiu

4

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18 March 2018

language of work or name

English

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publication date

1 July 2013

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18 March 2018

number of pages

5

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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18 March 2018

volume

453

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18 March 2018

issue

1

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18 March 2018

page(s)

147-151

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18 March 2018

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling

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Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

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NAADP mobilizes calcium from acidic organelles through two-pore channels

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A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose

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The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores

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21 January 2018

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21 January 2018

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An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals

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Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.

21 January 2018

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21 January 2018

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NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing

21 January 2018

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Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1

21 January 2018

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Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure

21 January 2018

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Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking

21 January 2018

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TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes

21 January 2018

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Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

21 January 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

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An N-terminal dileucine motif directs two-pore channels to the tonoplast of plant cells

21 January 2018

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Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels

21 January 2018

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N terminus is key to the dominant negative suppression of Ca(V)2 calcium channels: implications for episodic ataxia type 2.

21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20130474

21 January 2018

Identifiers

DOI

10.1042/BJ20130474

1 reference

18 March 2018

1 reference

18 March 2018