(Q50858312)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Meike Vogler

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

David Dinsdale

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Gerald M Cohen

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

English

0 references

publication date

4 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Haematology

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

163

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

139-142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23826785%20AND%20SRC:MED&resulttype=core&format=json

The Bcl2 family: regulators of the cellular life-or-death switch

4 March 2020

cites work

1 reference

Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

21 January 2018

1 reference

Programmed anuclear cell death delimits platelet life span.

21 January 2018

1 reference

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins

21 January 2018

1 reference

Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease

21 January 2018

1 reference

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

21 January 2018

1 reference

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

21 January 2018

1 reference