(Q50868692)

24 March 2018

title

Blocking von Willebrand factor for treatment of cutaneous inflammation. (English)

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4

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Dietmar Vestweber

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author name string

Carina Hillgruber

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Annika K Steingräber

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Birgit Pöppelmann

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Jerry Ware

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Bernhard Nieswandt

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Stefan W Schneider

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Tobias Goerge

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language of work or name

English

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publication date

28 June 2013

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Journal of Investigative Dermatology

published in

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volume

134

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issue

1

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page(s)

77-86

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Biochemistry and genetics of von Willebrand factor

cites work

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12 December 2020

Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases

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von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

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The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression

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Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

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Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

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von Willebrand factor promotes leukocyte extravasation

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2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

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Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura

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Localized reduction of atherosclerosis in von Willebrand factor-deficient mice

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von Willebrand factor: more than a regulator of hemostasis and thrombosis

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Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells

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Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress

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A role for platelets and endothelial selectins in tumor necrosis factor-alpha-induced leukocyte recruitment in the brain microvasculature

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Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

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Cutaneous leukocytoclastic vasculitis. Serial histopathologic evaluation demonstrates the dynamic nature of the infiltrate

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Von Willebrand factor deficiency and atherosclerosis

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Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

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Cutaneous small-vessel vasculitis

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Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice

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Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice

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Solid-phase von Willebrand factor contains a conformationally active RGD motif that mediates endothelial cell adhesion through the alpha v beta 3 receptor

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Pathogenesis of leukocytoclastic vasculitis.

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12 December 2020

Correction of bleeding symptoms in von Willebrand factor-deficient mice by liver-expressed von Willebrand factor mutants.

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Processing of von Willebrand factor by ADAMTS-13.

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12 December 2020

Von Willebrand factor, ADAMTS13 activity, TNF-α and their relationships in patients with chronic kidney disease

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12 December 2020

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

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12 December 2020

ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion

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Platelet glycoprotein Ib alpha supports experimental lung metastasis

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12 December 2020

Basal secretion of von Willebrand factor from human endothelial cells

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12 December 2020

P-selectin glycoprotein ligand 1 and beta2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor

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12 December 2020

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion.

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12 December 2020

Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome

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Deficiency of von Willebrand factor protects mice from ischemic stroke

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What a polyclonal antibody sees in von Willebrand factor

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12 December 2020

Getting to the site of inflammation: the leukocyte adhesion cascade updated

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Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice

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ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice.

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12 December 2020

The anti-von Willebrand factor aptamer ARC1779 increases von Willebrand factor levels and platelet counts in patients with type 2B von Willebrand disease

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Cell biology of von Willebrand factor

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12 December 2020

von Willebrand factor: an emerging target in stroke therapy.

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A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

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Mechanisms of platelet and leukocyte recruitment in experimental colitis

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Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells

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12 December 2020

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12 December 2020

Targeting von Willebrand factor and platelet glycoprotein Ib receptor

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12 December 2020

ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions

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12 December 2020

Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease

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12 December 2020

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

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12 December 2020

Inflammation induces hemorrhage in thrombocytopenia

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12 December 2020

Identifiers

DOI

10.1038/JID.2013.292

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24 March 2018

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24 March 2018