(Q50871558)

24 March 2018

title

Kv1.3 blockers ameliorate allergic contact dermatitis by preferentially suppressing effector memory T cells in a rat model. (English)

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allergic contact dermatitis

main subject

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A Ueyama

1

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K Imura

2

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E Kasai-Yamamoto

3

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N Tai

4

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M Nagira

5

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M Shichijo

6

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K Yasui

7

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publication date

1 December 2013

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Clinical and Experimental Dermatology

published in

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volume

38

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issue

8

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page(s)

897-903

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Molecular properties and physiological roles of ion channels in the immune system

cites work

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Ion channels in the immune system as targets for immunosuppression

21 January 2018

1 reference

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

21 January 2018

1 reference

Functional subsets of memory T cells identified by CCR7 expression

21 January 2018

1 reference

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

1 reference

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

21 January 2018

1 reference

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

21 January 2018

1 reference

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

21 January 2018

1 reference

The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation

21 January 2018

1 reference

Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis

21 January 2018

1 reference

The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.

21 January 2018

1 reference

CD8+ T cells are effector cells of contact dermatitis to common skin allergens in mice.

21 January 2018

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Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis.

21 January 2018

1 reference

Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases

21 January 2018

1 reference

IL-18 binding protein protects against contact hypersensitivity

21 January 2018

1 reference

A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes

21 January 2018

1 reference

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CED.12097

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24 March 2018

PubMed ID

24252082

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24 March 2018