(Q50876082)

24 March 2018

title

NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A. (English)

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24 March 2018

author name string

Moon-Taek Park

1

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24 March 2018

Eun-Taex Oh

2

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24 March 2018

Min-Jeong Song

3

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24 March 2018

Hyemi Lee

4

1 reference

24 March 2018

Eun Kyung Choi

5

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24 March 2018

Heon Joo Park

6

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24 March 2018

language of work or name

English

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publication date

26 June 2013

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24 March 2018

published in

Carcinogenesis

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24 March 2018

volume

34

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24 March 2018

issue

11

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24 March 2018

page(s)

2470-2485

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24 March 2018

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

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Sister chromatid tension and the spindle assembly checkpoint

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Losing balance: the origin and impact of aneuploidy in cancer

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Targeted and nontargeted effects of ionizing radiation that impact genomic instability

21 January 2018

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Karyotypic instability and centrosome aberrations in the progeny of finite life-span human mammary epithelial cells exposed to sparsely or densely ionizing radiation

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Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

21 January 2018

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21 January 2018

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Centrosome aberrations: cause or consequence of cancer progression?

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Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

21 January 2018

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Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

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Coordination of centrosome homeostasis and DNA repair is intact in MCF-7 and disrupted in MDA-MB 231 breast cancer cells

21 January 2018

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Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers

21 January 2018

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Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage

21 January 2018

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DNA mismatch repair and Chk1-dependent centrosome amplification in response to DNA alkylation damage.

21 January 2018

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Novel pathway of centrosome amplification that does not require DNA lesions.

21 January 2018

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Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

21 January 2018

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DNA damage induces Chk1-dependent centrosome amplification.

21 January 2018

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Aurora-A - a guardian of poles

21 January 2018

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Aurora A is essential for early embryonic development and tumor suppression

21 January 2018

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On the role of aurora-A in centrosome function

21 January 2018

1 reference

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

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Aurora kinases as targets for cancer therapy

21 January 2018

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Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen

21 January 2018

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Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors

21 January 2018

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Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer

21 January 2018

1 reference

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Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

1 reference

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Induction of centrosome amplification and chromosome instability in human bladder cancer cells by p53 mutation and cyclin E overexpression

21 January 2018

1 reference

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Requirements for the destruction of human Aurora-A.

21 January 2018

1 reference

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Control of Aurora-A stability through interaction with TPX2.

21 January 2018

1 reference

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21 January 2018

Radiation carcinogenesis

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The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase

21 January 2018

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β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells

21 January 2018

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A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis

21 January 2018

1 reference

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Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer

21 January 2018

1 reference

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Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

Apoptosis regulation in tetraploid cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

21 January 2018

p53: guardian of ploidy

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

Radiation-induced cell death mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

NAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT225

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGT225

1 reference

24 March 2018

1 reference

24 March 2018