(Q50896275)

24 March 2018

title

Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies. (English)

1 reference

24 March 2018

1 reference

Di Huang

1

1 reference

24 March 2018

Menglei Xia

2

1 reference

24 March 2018

Shanshan Li

3

1 reference

24 March 2018

Jianping Wen

4

1 reference

24 March 2018

Xiaoqiang Jia

5

1 reference

24 March 2018

publication date

19 June 2013

1 reference

24 March 2018

Journal of Industrial Microbiology & Biotechnology

published in

1 reference

24 March 2018

volume

40

1 reference

24 March 2018

issue

9

1 reference

24 March 2018

page(s)

1023-1037

1 reference

24 March 2018

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli.

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Improvement of FK506 production in Streptomyces tsukubaensis by genetic enhancement of the supply of unusual polyketide extender units via utilization of two distinct site-specific recombination systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

In silico identification of gene amplification targets for improvement of lycopene production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Overexpression of glucose-6-phosphate dehydrogenase enhances riboflavin production in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Colorimetric Method for Determination of Sugars and Related Substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Origin of the allyl group in FK506 biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Novel chemobiosynthetic approach for exclusive production of FK506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

The future of industrial antibiotic production: from random mutagenesis to synthetic biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Biochemical characterization of the SgcA1 alpha-D-glucopyranosyl-1-phosphate thymidylyltransferase from the enediyne antitumor antibiotic C-1027 biosynthetic pathway and overexpression of sgcA1 in Streptomyces globisporus to improve C-1027 productio

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

FK-506--a novel immunosuppressant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Effects of methylmalonyl-CoA mutase gene knockouts on erythromycin production in carbohydrate-based and oil-based fermentations of Saccharopolyspora erythraea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Engineering precursor flow for increased erythromycin production in Aeromicrobium erythreum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Methods for characterization of Streptomyces species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Ascomycin and FK506: pharmacology and therapeutic potential as anticonvulsants and neuroprotectants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Regulation of tacrolimus production by altering primary source of carbons and amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Novel two-component systems implied in antibiotic production in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1301-7

Effect of different biosynthetic precursors on the production of nargenicin A1 from metabolically engineered Nocardia sp. CS682.

21 January 2018

1 reference

12 December 2020

Increasing the efficiency of heterologous promoters in actinomycetes

1 reference

12 December 2020

Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase.

1 reference

12 December 2020

Chorismate mutase from Streptomyces aureofaciens: a heat-stable enzyme.

1 reference

12 December 2020

In silico aided metabolic engineering of Streptomyces roseosporus for daptomycin yield improvement

1 reference

12 December 2020

Effect of amino acids on rapamycin biosynthesis by Streptomyces hygroscopicus

1 reference

12 December 2020

Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis

1 reference

12 December 2020

Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520

1 reference

12 December 2020

Exogenous shikimic acid stimulates rapamycin biosynthesis in Streptomyces hygroscopicus

1 reference

12 December 2020

Metabolic flux analysis and principal nodes identification for daptomycin production improvement by Streptomyces roseosporus

1 reference

12 December 2020

10.1007/S10295-013-1301-7

Identifiers

DOI

1 reference

24 March 2018

1 reference

24 March 2018