(Q50915986)

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title

Lantibiotic engineering: molecular characterization and exploitation of lantibiotic-synthesizing enzymes for peptide engineering. (English)

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author name string

Jun-ichi Nagao

1

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Yuji Aso

2

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Kouki Shioya

3

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Jiro Nakayama

4

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Kenji Sonomoto

5

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publication date

1 January 2007

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Journal of Molecular Microbiology and Biotechnology

published in

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volume

13

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issue

4

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page(s)

235-242

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Maturation pathway of nisin and other lantibiotics: post-translationally modified antimicrobial peptides exported by gram-positive bacteria

cites work

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Biosynthesis and mode of action of lantibiotics.

21 January 2018

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Biosynthesis and biological activities of lantibiotics with unique post-translational modifications

21 January 2018

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A novel lantibiotic, nukacin ISK-1, of Staphylococcus warneri ISK-1: cloning of the structural gene and identification of the structure

21 January 2018

1 reference

Characterization of a gene cluster of Staphylococcus warneri ISK-1 encoding the biosynthesis of and immunity to the lantibiotic, nukacin ISK-1.

21 January 2018

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Description of complete DNA sequence of two plasmids from the nukacin ISK-1 producer, Staphylococcus warneri ISK-1.

21 January 2018

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Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

21 January 2018

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Localization and interaction of the biosynthetic proteins for the lantibiotic, Nukacin ISK-1.

21 January 2018

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Lantibiotic biosynthesis: interactions between prelacticin 481 and its putative modification enzyme, LctM

21 January 2018

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Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli

21 January 2018

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NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides.

21 January 2018

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Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin

21 January 2018

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Lysine-oriented charges trigger the membrane binding and activity of nukacin ISK-1.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000104749

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