(Q50921450)

English

Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA).

scientific article published on 21 October 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/26489704

Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA). (English)

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Europe PubMed Central

PubMed publication ID

25 March 2018

http://europepmc.org/abstract/MED/26489704

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Kim Hørslev-Petersen

1

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5 June 2020

Torkell Ellingsen

6

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5 June 2020

Hanne Lindegaard

8

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5 June 2020

Merete Lund Hetland

2

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5 June 2020

Lykke M Ørnbjerg

3

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5 June 2020

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P Junker

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5 June 2020

J Pødenphant

5

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5 June 2020

P Ahlquist

7

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5 June 2020

A Linauskas

9

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5 June 2020

A Schlemmer

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5 June 2020

M Y Dam

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5 June 2020

I Hansen

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5 June 2020

T Lottenburger

13

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5 June 2020

C G Ammitzbøll

14

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5 June 2020

A Jørgensen

15

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5 June 2020

S B Krintel

16

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5 June 2020

J Raun

17

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5 June 2020

J S Johansen

18

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5 June 2020

M Østergaard

19

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5 June 2020

K Stengaard-Pedersen

20

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5 June 2020

OPERA Study-Group

21

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5 June 2020

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publication date

21 October 2015

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25 March 2018

http://europepmc.org/abstract/MED/26489704

Annals of the Rheumatic Diseases

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5 June 2020

75

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5 June 2020

9

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5 June 2020

1645-1653

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5 June 2020

State-of-the-art: rheumatoid arthritis

1 reference

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21 January 2018

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21 January 2018

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

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21 January 2018

Radiographic progression and remission rates in early rheumatoid arthritis - MRI bone oedema and anti-CCP predicted radiographic progression in the 5-year extension of the double-blind randomised CIMESTRA trial.

1 reference

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21 January 2018

Combination treatment with methotrexate, cyclosporine, and intraarticular betamethasone compared with methotrexate and intraarticular betamethasone in early active rheumatoid arthritis: An investigator-initiated, multicenter, randomized, double-blind

1 reference

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21 January 2018

MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA)

1 reference

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21 January 2018

Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-

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American College of Rheumatology/European League Against Rheumatism Provisional Definition of Remission in Rheumatoid Arthritis for Clinical Trials

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Shared care or nurse consultations as an alternative to rheumatologist follow-up for rheumatoid arthritis (RA) outpatients with stable low disease-activity RA: cost-effectiveness based on a 2-year randomized trial

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21 January 2018

What factors influence the health status of patients with rheumatoid arthritis measured by the SF-12v2 Health Survey and the Health Assessment Questionnaire?

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DANBIO--powerful research database and electronic patient record

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Induction therapy with adalimumab plus methotrexate for 24 weeks followed by methotrexate monotherapy up to week 48 versus methotrexate therapy alone for DMARD-naive patients with early rheumatoid arthritis: HIT HARD, an investigator-initiated study

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Clinical, functional and radiographic consequences of achieving stable low disease activity and remission with adalimumab plus methotrexate or methotrexate alone in early rheumatoid arthritis: 26-week results from the randomised, controlled OPTIMA s

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Treating to a target in established active rheumatoid arthritis patients receiving a tumor necrosis factor inhibitor: results from a real-world cluster-randomized adalimumab trial

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Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results of the HOPEFUL-1 trial.

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A two-step treatment strategy trial in patients with early arthritis aimed at achieving remission: the IMPROVED study

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21 January 2018

Longterm effect of delaying combination therapy with tumor necrosis factor inhibitor in patients with aggressive early rheumatoid arthritis: 10-year efficacy and safety of adalimumab from the randomized controlled PREMIER trial with open-label exten

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21 January 2018

Short- and long-term efficacy of intra-articular injections with betamethasone as part of a treat-to-target strategy in early rheumatoid arthritis: impact of joint area, repeated injections, MRI findings, anti-CCP, IgM-RF and CRP

1 reference

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21 January 2018

Analysis of integrated radiographic data from two long-term, open-label extension studies of adalimumab for the treatment of rheumatoid arthritis

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21 January 2018

What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review

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Does sonographic needle guidance affect the clinical outcome of intraarticular injections?

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Periarticular and generalised bone loss in patients with early rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial

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Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

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10.1136/ANNRHEUMDIS-2015-208166

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489704%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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24 November 2022

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5 June 2020

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