(Q50972002)

26 March 2018

title

CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH. (English)

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26 March 2018

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11

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26 March 2018

Weizhi Ji

15

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26 March 2018

author name string

Yu Kang

1

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26 March 2018

Bo Zheng

2

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26 March 2018

Bin Shen

3

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26 March 2018

Yongchang Chen

4

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26 March 2018

Lei Wang

5

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26 March 2018

Jianying Wang

6

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26 March 2018

Yuyu Niu

7

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26 March 2018

Yiqiang Cui

8

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26 March 2018

Jiankui Zhou

9

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26 March 2018

Hong Wang

10

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26 March 2018

Bian Hu

12

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26 March 2018

Qi Zhou

13

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26 March 2018

Jiahao Sha

14

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26 March 2018

Xingxu Huang

16

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26 March 2018

publication date

13 October 2015

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26 March 2018

published in

Human Molecular Genetics

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26 March 2018

volume

24

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26 March 2018

issue

25

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26 March 2018

page(s)

7255-7264

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26 March 2018

Altering the genome by homologous recombination

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Progress and prospects for genetic modification of nonhuman primate models in biomedical research

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Cas9 as a versatile tool for engineering biology

21 January 2018

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Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

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Germline acquisition of Cas9/RNA-mediated gene modifications in monkeys

21 January 2018

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The DAX1 mutation in a patient with hypogonadotropic hypogonadism and adrenal hypoplasia congenita causes functional disruption of induction of spermatogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

Hypogonadotropic hypogonadism in subjects with DAX1 mutations

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

An alternate translation initiation site circumvents an amino-terminal DAX1 nonsense mutation leading to a mild form of X-linked adrenal hypoplasia congenita

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

Four Japanese patients with adrenal hypoplasia congenita and hypogonadotropic hypogonadism caused by DAX-1 gene mutations: mutant DAX-1 failed to repress steroidogenic acute regulatory protein (StAR) and luteinizing hormone beta-subunit gene promote

21 January 2018

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Birth after TESE-ICSI in a man with hypogonadotropic hypogonadism and congenital adrenal hypoplasia linked to a DAX-1 (NR0B1) mutation

21 January 2018

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Dax1 regulates testis cord organization during gonadal differentiation

21 January 2018

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MVH in piRNA processing and gene silencing of retrotransposons

21 January 2018

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GATA4 regulates Sertoli cell function and fertility in adult male mice

21 January 2018

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Role of Ahch in gonadal development and gametogenesis

21 January 2018

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Analysis of DAX1 (NR0B1) and steroidogenic factor-1 (NR5A1) in children and adults with primary adrenal failure: ten years' experience

21 January 2018

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Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells

21 January 2018

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AMH/MIS: what we know already about the gene, the protein and its regulation

21 January 2018

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Sex determination and the control of Sox9 expression in mammals

21 January 2018

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The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

21 January 2018

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The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance

21 January 2018

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Wnt/Frizzled signaling in the vasculature: new angiogenic factors in sight

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning.

21 January 2018

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Novel activities of CYP11A1 and their potential physiological significance.

21 January 2018

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Genome modification by CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

Dax1 is required for testis determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

A phenotypic spectrum of sexual development in Dax1 (Nr0b1)-deficient mice: consequence of the C57BL/6J strain on sex determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

Construction of a proteome profile and functional analysis of the proteins involved in the initiation of mouse spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

Establishment of a proteomic profile associated with gonocyte and spermatogonial stem cell maturation and differentiation in neonatal mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV425

21 January 2018

Identifiers

DOI

10.1093/HMG/DDV425

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26 March 2018

PubMed ID

26464492

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26 March 2018