(Q51027178)

English

IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKL

scientific article published on April 10, 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKL (English)

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

author name string

Michele Kaczmarek

2

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

Mehrdad Tondravi

4

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

Jose L. Moreno

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689929

23 December 2023

Achsah D. Keegan

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12689929

23 December 2023

language of work or name

0 references

publication date

10 April 2003

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

full work available at URL

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

102

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

1078-1086

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

3

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

Bifurcation of osteoclasts and dendritic cells from common progenitors

1

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Multinucleated giant cells

3

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4 Reversibly Inhibits Osteoclastogenesis via Inhibition of NF-κB and Mitogen-activated Protein Kinase Signaling

5

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4 as a potent inhibitor of bone resorption

6

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB

7

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Th1-Th2: reliable paradigm or dangerous dogma?

10

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

The IL-4 receptor: signaling mechanisms and biologic functions

11

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4. A regulatory protein

12

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

13

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Combined stimulation with the T helper cell type 2 cytokines interleukin (IL)-4 and IL-10 induces mouse mast cell apoptosis

14

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin 4 inhibits murine osteoclast formation in vitro.

15

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4 inhibits spontaneous and parathyroid hormone-related protein-stimulated osteoclast formation in mice.

16

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Effects of interleukin-4 on the formation of macrophages and osteoclast-like cells

17

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Inhibitory effect of interleukin-4 on osteoclast-like cell formation in mouse bone marrow culture.

18

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Short-term treatment of recombinant murine interleukin-4 rapidly inhibits bone formation in normal and ovariectomized mice

19

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4 modulates osteoclast differentiation and inhibits the formation of resorption pits in mouse osteoclast cultures

21

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

23

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

RANK-L and RANK: T cells, bone loss, and mammalian evolution

24

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

25

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

26

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

27

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

NF-kappa B activation plays an important role in the IL-4-induced protection from apoptosis

28

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.

29

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction

30

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Preparation and characterization of a mouse osteoclast-like multinucleated cell population.

31

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro

32

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

33

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis

34

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Osteoporosis induced in mice by overproduction of interleukin 4.

35

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells

36

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover

37

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

39

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

40

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

RANK is essential for osteoclast and lymph node development

41

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Interleukin-4 suppression of tumor necrosis factor alpha-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-kappaB

42

1 reference

10.1182/BLOOD-2002-11-3437

https://api.crossref.org/works/10.1182/BLOOD-2002-11-3437

23 December 2023

Identifiers

10.1182/BLOOD-2002-11-3437

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/12689929

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q51027178&oldid=2036311836"