(Q51030175)

English

PD168077, a D(4) receptor agonist, reverses object recognition deficits in rats: potential role for D(4) receptor mechanisms in improving cognitive dysfunction in schizophrenia.

scientific article published on 18 November 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

PD168077, a D(4) receptor agonist, reverses object recognition deficits in rats: potential role for D(4) receptor mechanisms in improving cognitive dysfunction in schizophrenia. (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

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cognitive dysfunction

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

author name string

Pooja Sood

1

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Nagi F Idris

2

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Susan Cole

3

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Ben Grayson

4

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Andrew M J Young

6

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

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publication date

18 November 2010

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Journal of Psychopharmacology

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

25

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

6

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

792-800

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat.

1 reference

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The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Phencyclidine-induced psychosis

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Facilitatory effect of the dopamine D4 receptor agonist PD168,077 on memory consolidation of an inhibitory avoidance learned response in C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

The object recognition task in rats and mice: a simple and rapid model in safety pharmacology to detect amnesic properties of a new chemical entity.

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21 January 2018

A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia

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Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: a placebo-controlled trial

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Glutamate and schizophrenia: beyond the dopamine hypothesis

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The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents.

1 reference

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21 January 2018

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

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Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia

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Schizophrenia and temporal lobe epilepsy. A neuropsychological analysis

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Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat.

1 reference

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21 January 2018

The dopamine hypothesis of schizophrenia: version III--the final common pathway

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21 January 2018

Effect of Phencyclidine in Chronic Schizophrenics

1 reference

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21 January 2018

Recent advances in the phencyclidine model of schizophrenia

1 reference

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21 January 2018

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys.

1 reference

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21 January 2018

Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1).

1 reference

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21 January 2018

Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial.

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https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia

1 reference

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21 January 2018

Catching up on schizophrenia: natural history and neurobiology

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https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

D(1)-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia.

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

PCP: from pharmacology to modelling schizophrenia

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Phencyclidine animal models of schizophrenia: approaches from abnormality of glutamatergic neurotransmission and neurodevelopment

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

NMDA receptor hypofunction model of schizophrenia

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Cellular localization and distribution of dopamine D(4) receptors in the rat cerebral cortex and their relationship with the cortical dopaminergic and noradrenergic nerve terminal networks

1 reference

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21 January 2018

Neuropsychological function in schizophrenia. Selective impairment in memory and learning

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: correlation with AMPA receptor subunit expression in rat hippocampus.

1 reference

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21 January 2018

Antipsychotic Drugs: Direct Correlation Between Clinical Potency and Presynaptic Action on Dopamine Neurons

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21 January 2018

Dopamine receptor pharmacology

1 reference

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21 January 2018

Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats--a preliminary investigation

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21 January 2018

Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors

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21 January 2018

Influence of gender on working and spatial memory in the novel object recognition task in the rat.

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21 January 2018

Aberrant regulation of NMDA receptors by dopamine D4 signaling in rats after phencyclidine exposure

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Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval.

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21 January 2018

The dopamine D4 receptors and mechanisms of antipsychotic atypicality.

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21 January 2018

Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat.

1 reference

https://api.crossref.org/works/10.1177%2F0269881110387840

21 January 2018

Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex

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21 January 2018

Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

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Identifiers

10.1177/0269881110387840

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/21088042

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