(Q51035349)

27 March 2018

title

Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages. (English)

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Andrew Churg

1

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Xiaoshan Wang

2

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Rong D Wang

3

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Scott C Meixner

4

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Edward L G Pryzdial

5

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Joanne L Wright

6

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publication date

29 March 2007

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American Journal of Respiratory Cell and Molecular Biology

published in

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volume

37

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issue

2

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page(s)

144-151

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The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years

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Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice

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α-1-Antitrypsin Ameliorates Cigarette Smoke–induced Emphysema in the Mouse

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Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: parallels with human disease.

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Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects

21 January 2018

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Inhibition of lipopolysaccharide-mediated human monocyte activation, in vitro, by alpha1-antitrypsin

21 January 2018

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Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse

21 January 2018

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Proteinase-activated receptor-1 regulation of macrophage elastase (MMP-12) secretion by serine proteinases

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Mechanisms of cigarette smoke induced increased airspace permeability

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Prolastin, a pharmaceutical preparation of purified human alpha1-antitrypsin, blocks endotoxin-mediated cytokine release

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A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

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alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis

21 January 2018

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State of the art. Apoptosis and cell homeostasis in chronic obstructive pulmonary disease

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Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-alpha fusion protein

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Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen

21 January 2018

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Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

21 January 2018

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The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): a milestone protein

21 January 2018

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Smoking increases tissue factor expression in atherosclerotic plaques: implications for plaque thrombogenicity

21 January 2018

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Association between alveolar macrophage plasminogen activator activity and indices of lung function in young cigarette smokers

21 January 2018

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Processing of tumour necrosis factor-α precursor by metalloproteinases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1165/RCMB.2006-0345OC

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27 March 2018

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27 March 2018