(Q51042662)

27 March 2018

title

The cytotoxicity of duocarmycin analogues is mediated through alkylation of DNA, not aldehyde dehydrogenase 1: a comment. (English)

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27 March 2018

author

Euphemia Leung

3

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27 March 2018

Frederik B. Pruijn

6

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27 March 2018

author name string

Moana Tercel

1

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27 March 2018

Sarah P McManaway

2

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27 March 2018

H D Sarath Liyanage

4

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27 March 2018

Guo-Liang Lu

5

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27 March 2018

language of work or name

English

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publication date

24 April 2013

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27 March 2018

Angewandte Chemie International Edition

published in

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volume

52

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27 March 2018

page(s)

5442-5446

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27 March 2018

issue

21

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27 March 2018

Fundamental relationships between structure, reactivity, and biological activity for the duocarmycins and CC-1065.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Chemical and biological explorations of the family of CC-1065 and the duocarmycin natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Duocarmycin analogues target aldehyde dehydrogenase 1 in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Glycosidic prodrugs of highly potent bifunctional duocarmycin derivatives for selective treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

The reversible DNA-alkylating activity of duocarmycin and its analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Alkaline gel electrophoresis of deoxyribonucleic acid photoreacted with trimethylpsoralen: rapid and sensitive detection of interstrand cross-links

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Repression of mutagenesis by Rad51D-mediated homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N3 DNA minor groove alkylators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Homologous recombination repair-dependent cytotoxicity of the benzotriazine di-N-oxide CEN-209: comparison with other hypoxia-activated prodrugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

In situ identification of putative cancer stem cells by multiplexing ALDH1, CD44, and cytokeratin identifies breast cancer patients with poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Heterogeneity of aldehyde dehydrogenase expression in lung cancer cell lines is revealed by Aldefluor flow cytometry-based assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Unsymmetrical DNA cross-linking agents: combination of the CBI and PBD pharmacophores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

Selective treatment of hypoxic tumor cells in vivo: phosphate pre-prodrugs of nitro analogues of the duocarmycins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201208373

21 January 2018

Identifiers

DOI

10.1002/ANIE.201208373

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27 March 2018

PubMed ID

23616474

1 reference

27 March 2018