(Q51095061)

29 March 2018

title

Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling. (English)

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29 March 2018

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Nathaniel Lal

1

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29 March 2018

Amy Pei-Ling Chiu

2

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29 March 2018

Fulong Wang

3

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29 March 2018

Dahai Zhang

4

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29 March 2018

Jocelyn Jia

5

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29 March 2018

Andrea Wan

6

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29 March 2018

Israel Vlodavsky

7

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29 March 2018

Bahira Hussein

8

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29 March 2018

Brian Rodrigues

9

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29 March 2018

publication date

17 March 2017

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29 March 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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29 March 2018

volume

312

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29 March 2018

issue

6

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29 March 2018

page(s)

H1163-H1175

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29 March 2018

Site-directed mutagenesis, proteolytic cleavage, and activation of human proheparanase

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Assessment of cardiac inflammation and remodeling during the development of streptozotocin-induced diabetic cardiomyopathy in vivo: a time course analysis.

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Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation

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Rodent models of diabetic cardiomyopathy.

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Cell death and diabetic cardiomyopathy

21 January 2018

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Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta

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Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

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Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications

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Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans

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The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease

21 January 2018

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Lipoprotein lipase mediated fatty acid delivery and its impact in diabetic cardiomyopathy

21 January 2018

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VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart.

21 January 2018

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21 January 2018

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VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats

21 January 2018

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Diabetic cardiomyopathy and its mechanisms: Role of oxidative stress and damage

21 January 2018

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Myocardial fatty acid metabolism in health and disease

21 January 2018

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Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

21 January 2018

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Lipoprotein lipase and its role in regulation of plasma lipoproteins and cardiac risk

21 January 2018

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Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

21 January 2018

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Lysophosphatidic acid-mediated augmentation of cardiomyocyte lipoprotein lipase involves actin cytoskeleton reorganization.

21 January 2018

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Myocardial substrate metabolism: implications for diabetic cardiomyopathy

21 January 2018

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Cardiac function in spontaneously hypertensive diabetic rats

21 January 2018

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The diabetic heart: metabolic causes for the development of a cardiomyopathy

21 January 2018

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Localization of lipoprotein lipase in the diabetic heart: regulation by acute changes in insulin.

21 January 2018

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Diabetes, hypertension, and cardiovascular disease: an update

21 January 2018

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Altered creatine kinase enzyme kinetics in diabetic cardiomyopathy. A(31)P NMR magnetization transfer study of the intact beating rat heart.

21 January 2018

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Cell communications in the heart.

21 January 2018

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Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress

21 January 2018

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Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid

21 January 2018

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Glucose-induced endothelial heparanase secretion requires cortical and stress actin reorganization.

21 January 2018

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21 January 2018

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Endothelial cell heparanase taken up by cardiomyocytes regulates lipoprotein lipase transfer to the coronary lumen after diabetes.

21 January 2018

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Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly

21 January 2018

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Intracoronary Cytoprotective Gene Therapy: A Study of VEGF-B167 in a Pre-Clinical Animal Model of Dilated Cardiomyopathy

21 January 2018

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Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

21 January 2018

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Glycogen synthase kinase-3beta regulates etoposide-induced apoptosis via Bcl-2 mediated caspase-3 activation in C3H10T1/2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00659.2016

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00659.2016

Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00659.2016

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

21 January 2018

1 reference

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10.1152/AJPHEART.00659.2016

21 January 2018

Identifiers

DOI

1 reference

29 March 2018

PubMed ID

28314760

1 reference

29 March 2018