(Q51115052)

30 March 2018

title

Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis. (English)

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30 March 2018

author

Luke L. Lairson

1

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30 March 2018

Andrew G. Watts

2

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30 March 2018

Warren Wakarchuk

3

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author name string

Stephen G Withers

4

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30 March 2018

publication date

22 October 2006

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30 March 2018

published in

Nature Chemical Biology

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30 March 2018

volume

2

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issue

12

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page(s)

724-728

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30 March 2018

https://scigraph.springernature.com/pub.10.1038/nchembio828

exact match

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beta-Mannosynthase: Synthesis of beta-Mannosides with a Mutant beta-Mannosidase We thank the Protein Engineering Network of Centres of Excellence of Canada and the Natural Sciences and Engineering Research Council of Canada for support. D.L.Z. thank

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Synthesis of amphiphilic lactosides that possess a lactosylceramide-mimicking N-acyl structure: alternative universal substrates for endo-type glycosylceramidases

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Engineering enzyme specificity by "substrate-assisted catalysis"

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Identifiers

DOI

10.1038/NCHEMBIO828

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30 March 2018

Dimensions Publication ID

1018809696

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30 March 2018