(Q51171807)

31 March 2018

title

The impacts of age and frailty on heart rate and sinoatrial node function. (English)

1 reference

31 March 2018

author

Susan Howlett

7

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31 March 2018

author name string

Motahareh Moghtadaei

1

1 reference

31 March 2018

Hailey J Jansen

2

1 reference

31 March 2018

Martin Mackasey

3

1 reference

31 March 2018

Sara A Rafferty

4

1 reference

31 March 2018

Oleg Bogachev

5

1 reference

31 March 2018

John L Sapp

6

1 reference

31 March 2018

Robert A Rose

8

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31 March 2018

language of work or name

English

0 references

publication date

6 September 2016

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31 March 2018

number of pages

22

1 reference

inferred from page(s)

published in

Journal of Physiology

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31 March 2018

volume

594

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31 March 2018

issue

23

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31 March 2018

page(s)

7105-7126

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31 March 2018

Pharmacological Strategies to Retard Cardiovascular Aging

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Impaired sinoatrial node function and increased susceptibility to atrial fibrillation in mice lacking natriuretic peptide receptor C.

8 September 2018

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Reliability of a Frailty Index Based on the Clinical Assessment of Health Deficits in Male C57BL/6J Mice

8 September 2018

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Importance of frailty in patients with cardiovascular disease

8 September 2018

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Age-associated abnormalities of intrinsic automaticity of sinoatrial nodal cells are linked to deficient cAMP-PKA-Ca(2+) signaling

8 September 2018

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Effects of natriuretic peptides on electrical conduction in the sinoatrial node and atrial myocardium of the heart.

8 September 2018

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Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate

8 September 2018

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Measuring frailty in heart failure: a community perspective

8 September 2018

1 reference

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A clinical frailty index in aging mice: comparisons with frailty index data in humans

8 September 2018

1 reference

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Frailty in elderly people

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Distinct patterns of constitutive phosphodiesterase activity in mouse sinoatrial node and atrial myocardium

8 September 2018

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The natriuretic peptides BNP and CNP increase heart rate and electrical conduction by stimulating ionic currents in the sinoatrial node and atrial myocardium following activation of guanylyl cyclase-linked natriuretic peptide receptors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Conduction barriers and pathways of the sinoatrial pacemaker complex: their role in normal rhythm and atrial arrhythmias

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

The frailty syndrome: a comprehensive review

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

A procedure for creating a frailty index based on deficit accumulation in aging mice.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Insights into sick sinus syndrome from an inducible mouse model.

8 September 2018

1 reference

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The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic Peptide

8 September 2018

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Frailty defined by deficit accumulation and geriatric medicine defined by frailty.

8 September 2018

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Outcome instruments to measure frailty: a systematic review

8 September 2018

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Complex interactions between the sinoatrial node and atrium during reentrant arrhythmias in the canine heart

8 September 2018

1 reference

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Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice

8 September 2018

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A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

8 September 2018

1 reference

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Structural remodelling of the sinoatrial node in obese old rats

8 September 2018

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Structural and functional evidence for discrete exit pathways that connect the canine sinoatrial node and atria.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

A standard procedure for creating a frailty index.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Genesis and regulation of the heart automaticity.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Blebbistatin: use as inhibitor of muscle contraction.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Altered heart rate and sinoatrial node function in mice lacking the cAMP regulator phosphoinositide 3-kinase-gamma

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs)

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Frailty in relation to the accumulation of deficits

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

New insights into pacemaker activity: promoting understanding of sick sinus syndrome

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Declining into failure: the age-dependent loss of the L-type calcium channel within the sinoatrial node

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Postganglionic nerve stimulation induces temporal inhibition of excitability in rabbit sinoatrial node.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Structure and function of matrix metalloproteinases and TIMPs

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Heterogeneity of action potential durations in isolated mouse left and right atria recorded using voltage-sensitive dye mapping

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Diagnosis and treatment of sick sinus syndrome

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Matrix metalloproteinases: regulation and dysregulation in the failing heart

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

The evaluation and management of bradycardia

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Primary prevention of sudden cardiac death in heart failure: will the solution be shocking?

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Cardiac pacemaking in the sinoatrial node

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5134407

Long-Term Risks of Death and Institutionalization of Elderly People in Relation to Deficit Accumulation at Age 70

8 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJP272979

Expression of Kir2.1 and Kir6.2 transgenes under the control of the α-MHC promoter in the sinoatrial and atrioventricular nodes in transgenic mice

21 January 2018

1 reference

12 December 2020

Not so fast! Sick sinus syndrome is a complex and incompletely understood disease that might prove hard to model in animals

1 reference

12 December 2020

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

1 reference

12 December 2020

Accumulation of deficits as a proxy measure of aging

1 reference

12 December 2020

Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution

1 reference

12 December 2020

1 reference

12 December 2020

Myocardial extra-cellular matrix and its regulation by metalloproteinases and their inhibitors

1 reference

12 December 2020

1 reference

12 December 2020

Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping

1 reference

12 December 2020

Ageing-dependent remodelling of ion channel and Ca2+clock genes underlying sino-atrial node pacemaking

1 reference

12 December 2020

Identifiers

DOI

10.1113/JP272979

1 reference

31 March 2018

release_mrpihzgytzgtdf5vauphzjaawm

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mrpihzgytzgtdf5vauphzjaawm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

5134407

0 references

1 reference

31 March 2018