(Q51173466)

English

Shift from surrogate end point to outcome trials: implications for cardiovascular safety assessment in development programs for antidiabetic drugs.

scientific article published on 23 November 2011

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

Shift from surrogate end point to outcome trials: implications for cardiovascular safety assessment in development programs for antidiabetic drugs. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

author name string

J F Marcinak

1

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

P Viswanathan

2

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

V Arora

3

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

L E Roebel

4

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

T R Strack

5

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

E Leifke

6

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

language of work or name

0 references

publication date

23 November 2011

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

Clinical Pharmacology & Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

91

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

3

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

514-520

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effects of intensive glucose lowering in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Glucose control and vascular complications in veterans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Impact of cardiovascular outcomes on the development and approval of medications for the treatment of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

An analysis of the impact of FDA's guidelines for addressing cardiovascular risk of drugs for type 2 diabetes on clinical development

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Long-term cardiac outcomes in renal transplant recipients receiving fluvastatin: the ALERT extension study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the cholesterol and recurrent events (CARE) trial. The Care Investiga

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Telmisartan, ramipril, or both in patients at high risk for vascular events

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Angiotensin-converting-enzyme inhibition in stable coronary artery disease

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of intensive statin therapy on clinical outcomes among patients undergoing percutaneous coronary intervention for acute coronary syndrome. PCI-PROVE IT: A PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombol

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

The QUinapril Ischemic Event Trial (QUIET): evaluation of chronic ACE inhibitor therapy in patients with ischemic heart disease and preserved left ventricular function

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Prevalence of coronary heart disease in the Framingham Offspring Study: role of lipoprotein cholesterols

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Comparative outcomes study of metformin intervention versus conventional approach the COSMIC Approach Study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Effect of a multifactorial intervention on mortality in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

A systematic review of event rates in clinical trials in diabetes mellitus: the importance of quantifying baseline cardiovascular disease history and proteinuria and implications for clinical trial design

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Trends in the risk for coronary heart disease among adults with diagnosed diabetes in the U.S.: findings from the National Health and Nutrition Examination Survey, 1999-2008.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Determining the most appropriate components for a composite clinical trial outcome

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Clinical risk stratification in the emergency department predicts long-term cardiovascular outcomes in a population-based cohort presenting with acute chest pain: primary results of the Olmsted county chest pain study.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in coll

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: prospective, population based study of British men

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

21 January 2018

Cause-specific mortality in a population-based study of diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

7 January 2021

based on heuristic

inferred from DOI database lookup

Coronary risk factors and plaque morphology in men with coronary disease who died suddenly

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

7 January 2021

based on heuristic

inferred from DOI database lookup

Persistent activation of coagulation mechanism in unstable angina and myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

7 January 2021

based on heuristic

inferred from DOI database lookup

The risk of cardiovascular death following the first acute ischaemic syndrome: experience in Kaunas between 1997 and 2001

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.257

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2011.257

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 March 2018

http://europepmc.org/abstract/MED/22113235

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q51173466&oldid=1455635392"