(Q51372033)

4 April 2018

title

Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults. (English)

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4 April 2018

author name string

Dimitrios Psachoulias

1

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4 April 2018

Maria Vertzoni

2

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4 April 2018

Konstantinos Goumas

3

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4 April 2018

Vasilios Kalioras

4

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4 April 2018

Stefania Beato

5

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4 April 2018

James Butler

6

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4 April 2018

Christos Reppas

7

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4 April 2018

publication date

15 June 2011

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4 April 2018

published in

Pharmaceutical Research

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4 April 2018

volume

28

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4 April 2018

issue

12

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4 April 2018

page(s)

3145-3158

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4 April 2018

Using measured pKa, LogP and solubility to investigate supersaturation and predict BCS class

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Drug supersaturation in simulated and human intestinal fluids representing different nutritional states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Predicting intestinal precipitation--a case example for a basic BCS class II drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Estimation of intragastric solubility of drugs: in what medium?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Biorelevant Media to Simulate Fluids in the Ascending Colon of Humans and Their Usefulness in Predicting Intracolonic Drug Solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Determination of intralumenal individual bile acids by HPLC with charged aerosol detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Physiological parameters for oral delivery and in vitro testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Characterization of fluids from the stomach and proximal jejunum in men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Postprandial changes in solubilizing capacity of human intestinal fluids for BCS class II drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Rapid conversion of API hydrates to anhydrous forms in aqueous media

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Using a novel multicompartment dissolution system to predict the effect of gastric pH on the oral absorption of weak bases with poor intrinsic solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Postprandial Evolution in Composition and Characteristics of Human Duodenal Fluids in Different Nutritional States

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Influence of sample characteristics on quantification of carbamazepine hydrate formation by X-ray powder diffraction and Raman spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0506-6

Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir

21 January 2018

1 reference

12 December 2020

The effects of food on the dissolution of poorly soluble drugs in human and in model small intestinal fluids

1 reference

12 December 2020

Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum.

1 reference

12 December 2020

Trends in active pharmaceutical ingredient salt selection based on analysis of the Orange Book database

1 reference

12 December 2020

10.1007/S11095-011-0506-6

Identifiers

DOI

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4 April 2018

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4 April 2018