(Q51476122)

5 April 2018

title

The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus). (English)

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5 April 2018

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1

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author name string

K Hofmann

2

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I Bähr

3

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5 April 2018

S Streck

4

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E Albrecht

5

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5 April 2018

D Wedekind

6

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E Mühlbauer

7

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publication date

15 April 2011

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5 April 2018

published in

Diabetologia

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5 April 2018

volume

54

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issue

7

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5 April 2018

page(s)

1831-1840

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2138-0

exact match

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cites work

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Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets.

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Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses

21 January 2018

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Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor

21 January 2018

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Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling

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Melatonin and type 2 diabetes - a possible link?

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Function and expression of melatonin receptors on human pancreatic islets

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Parallel signaling pathways of melatonin in the pancreatic beta-cell

21 January 2018

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Melatonin stimulates inositol-1,4,5-trisphosphate and Ca2+ release from INS1 insulinoma cells

21 January 2018

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Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells

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Modulation of the cGMP signaling pathway by melatonin in pancreatic beta-cells

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Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status

21 January 2018

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Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats

21 January 2018

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Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy

21 January 2018

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Adrenoceptor expression and diurnal rhythms of melatonin and its precursors in the pineal gland of type 2 diabetic goto-kakizaki rats

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Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes

21 January 2018

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Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity

21 January 2018

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Metabolic effects of melatonin on oxidative stress and diabetes mellitus

21 January 2018

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Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat.

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Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels.

21 January 2018

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Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: metabolic alterations.

21 January 2018

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Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women

21 January 2018

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Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats

21 January 2018

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The LEW.1AR1/Ztm-iddm rat: a new model of spontaneous insulin-dependent diabetes mellitus

21 January 2018

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Indication of circadian oscillations in the rat pancreas

21 January 2018

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Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

21 January 2018

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Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene

21 January 2018

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Protective effect of melatonin on beta-cell damage in streptozotocin-induced diabetes in rats

21 January 2018

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Experimentally-induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster.

21 January 2018

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Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections.

21 January 2018

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21 January 2018

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Long-term enteral administration of melatonin reduces plasma insulin and increases expression of pineal insulin receptors in both Wistar and type 2-diabetic Goto-Kakizaki rats

21 January 2018

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Insulin modulates norepinephrine-mediated melatonin synthesis in cultured rat pineal gland

21 January 2018

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Insulin temporal sensitivity and its signaling pathway in the rat pineal gland.

21 January 2018

1 reference

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Decrease in catechol-O-methyltransferase activity in the liver of streptozotocin-induced diabetic rats

21 January 2018

1 reference

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Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

21 January 2018

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Oxidative stress: the vulnerable beta-cell

21 January 2018

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Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations

21 January 2018

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12 December 2020

Impaired circadian modulation of sympathovagal activity in diabetes. A possible explanation for altered temporal onset of cardiovascular disease

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12 December 2020

Evidence for the expression of both the MT1- and in addition, the MT2-melatonin receptor, in the rat pancreas, islet and beta-cell

1 reference

12 December 2020

Effects of streptozotocin-induced diabetes on heart rate, blood pressure and cardiac autonomic nervous control

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12 December 2020

Adrenal catecholamine metabolism and myocardial adrenergic receptors in streptozotocin diabetic rats

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12 December 2020

Plasma Corticosterone, Motor Activity and Metabolic Circadian Patterns in Streptozotocin-Induced Diabetic Rats

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12 December 2020

Diabetes induces changes in melatonin concentrations in peripheral tissues of rat.

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12 December 2020

Development of diabetes in the non-obese NIDDM rat (GK rat)

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12 December 2020

Effect of pinealectomy on liver insulin and glucagon receptor concentrations in the rat

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12 December 2020

Melatonin, endocrine pancreas and diabetes.

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12 December 2020

Release of catecholamines is increased but does not contribute to the impaired insulin secretion in the perfused pancreata of diabetic rats

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12 December 2020

10.1007/S00125-011-2138-0

Identifiers

DOI

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5 April 2018

PubMed ID

21491159

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5 April 2018