(Q51478323)

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Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

scientific article published on 13 February 2007

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes. (English)

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

type 2 diabetes

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Amalia Gastaldelli

3

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

author name string

Kenneth Cusi

1

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

Sangeeta Kashyap

2

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

Mandeep Bajaj

4

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

Eugenio Cersosimo

5

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

publication date

13 February 2007

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

American Journal of Physiology - Endocrinology and Metabolism

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

292

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

6

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Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

E1775-81

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders.

1 reference

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Sustained reduction in plasma free fatty acid concentration improves insulin action without altering plasma adipocytokine levels in subjects with strong family history of type 2 diabetes

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The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivo

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Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

1 reference

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

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Obesity and insulin resistance in humans: a dose-response study.

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The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

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Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans

1 reference

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21 January 2018

Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

1 reference

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21 January 2018

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

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21 January 2018

Effect of fatty acids on glucose production and utilization in man

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beta-Cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis

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21 January 2018

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents

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21 January 2018

Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.

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21 January 2018

The nicotinic acid receptor--a new mechanism for an old drug

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00624.2006

21 January 2018

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00624.2006

21 January 2018

Fuel selection in human skeletal muscle in insulin resistance: a reexamination

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Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome

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Relationship between insulin-mediated glucose disposal and lipid metabolism in man.

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21 January 2018

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

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21 January 2018

Glucose-induced insulin hypersecretion in lipid-infused healthy subjects is associated with a decrease in plasma norepinephrine concentration and urinary excretion

1 reference

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21 January 2018

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

1 reference

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21 January 2018

Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00624.2006

21 January 2018

Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes.

1 reference

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21 January 2018

Nicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid content

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21 January 2018

Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects

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21 January 2018

Molecular identification of nicotinic acid receptor

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21 January 2018

Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation.

1 reference

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21 January 2018

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

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21 January 2018

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

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Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance

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Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia

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Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

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Molecular identification of high and low affinity receptors for nicotinic acid

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Effect of pioglitazone on pancreatic beta-cell function and diabetes risk in Hispanic women with prior gestational diabetes

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

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21 January 2018

Identifiers

10.1152/AJPENDO.00624.2006

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17299078

ResearchGate publication ID

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