(Q51494026)

5 April 2018

title

The molecular and mathematical basis of Waddington's epigenetic landscape: a framework for post-Darwinian biology? (English)

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5 April 2018

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Sui Huang

1

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5 April 2018

language of work or name

English

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publication date

18 November 2011

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5 April 2018

published in

BioEssays

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5 April 2018

volume

34

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5 April 2018

issue

2

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5 April 2018

page(s)

149-157

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5 April 2018

Genetics and the origin of species: an introduction

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https://api.crossref.org/works/10.1002%2FBIES.201100031

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Back to the biology in systems biology: what can we learn from biomolecular networks?

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Waddington’s Unfinished Critique of Neo-Darwinian Genetics: Then and Now

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The coming Kuhnian revolution in biology

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An extended synthesis for evolutionary biology

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The frailty of adaptive hypotheses for the origins of organismal complexity

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The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme

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Integrating historical and mechanistic biology enhances the study of adaptation

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Genotype-phenotype mapping and the end of the 'genes as blueprint' metaphor

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A systems biology view of evolutionary genetics: network-driven processes incorporate much more variation than evolutionary genetics can handle. This variation is hard to formalise but allows fast change.

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Structure and evolution of protein interaction networks: a statistical model for link dynamics and gene duplications

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The evolutionary dynamics of evolvability in a gene network model

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Functional and evolutionary inference in gene networks: does topology matter?

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Robustness and evolvability in genetic regulatory networks

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Neutralism and selectionism: a network-based reconciliation

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Structure and evolution of transcriptional regulatory networks

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Topological evolution of dynamical networks: global criticality from local dynamics.

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Network biology: understanding the cell's functional organization

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Biological networks: the tinkerer as an engineer.

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Between "design" and "bricolage": genetic networks, levels of selection, and adaptive evolution

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Teleonomic mechanisms in cellular metabolism, growth, and differentiation

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Metabolic stability and epigenesis in randomly constructed genetic nets

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Non-genetic heterogeneity of cells in development: more than just noise

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Functional roles for noise in genetic circuits

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Conrad Hal Waddington: the last Renaissance biologist?

21 January 2018

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Reprogramming cell fates: reconciling rarity with robustness

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DNA methylation and histone modifications: teaming up to silence genes

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Dynamic nucleosomes and gene transcription

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Chromatin modifications and their function

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The Language of Histone Crosstalk

21 January 2018

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Do chromatin loops provide epigenetic gene expression states?

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Spatial epigenetics: linking nuclear structure and function in higher eukaryotes

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Chromatin higher-order structures and gene regulation

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The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation

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Homeostasis and Differentiation in Random Genetic Control Networks

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

21 January 2018

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Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways

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Waddington's canalization revisited: developmental stability and evolution

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Understanding gene circuits at cell-fate branch points for rational cell reprogramming

21 January 2018

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Emerging principles of regulatory evolution

21 January 2018

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Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective

21 January 2018

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On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment.

21 January 2018

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The Baldwin effect and genetic assimilation: revisiting two mechanisms of evolutionary change mediated by phenotypic plasticity

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201100031

The Changing Concept of Epigenetics

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201100031

Systems-level dynamic analyses of fate change in murine embryonic stem cells

21 January 2018

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Creation and implications of a phenome-genome network

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201100031

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201100031

21 January 2018

Identifiers

DOI

10.1002/BIES.201100031

1 reference

5 April 2018

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5 April 2018