(Q51494284)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Use of human germline genes in a CDR homology-based approach to antibody humanization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

William Ying Khee Hwang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Juan C Almagro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Timothy N Buss

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Philip Tan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Jefferson Foote

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

publication date

1 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

volume

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

page(s)

35-42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15848073%20AND%20SRC:MED&resulttype=core&format=json

A humanized antibody that binds to the interleukin 2 receptor

11 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Canonical structures for the hypervariable regions of immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Structural repertoire of the human VH segments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

The structural repertoire of the human V kappa domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Standard conformations for the canonical structures of immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

The human immunoglobulin kappa variable (IGKV) genes and joining (IGKJ) segments.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

The human immunoglobulin heavy variable genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

"Superhumanized" antibodies: reduction of immunogenic potential by complementarity-determining region grafting with human germline sequences: application to an anti-CD28

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

The differences between the structural repertoires of VH germ-line gene segments of mice and humans: implication for the molecular mechanism of the immune response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Identification of specificity-determining residues in antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Identification of differences in the specificity-determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody repertoires.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Amino acid substitution matrices from protein blocks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Antibody-antigen interactions: contact analysis and binding site topography.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Gene synthesis and expression in E. coli for pump, a human matrix metalloproteinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

High level Escherichia coli expression and production of a bivalent humanized antibody fragment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Antibody framework residues affecting the conformation of the hypervariable loops

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Reshaping a therapeutic CD4 antibody

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

The integrity of the ball-and-socket joint between V and C domains is essential for complete activity of a humanized antibody.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Reshaping human antibodies for therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Humanization of an anti-p185HER2 antibody for human cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004

Identification of framework residues required to restore antigen binding during reshaping of a monoclonal antibody against the glycoprotein gB of human cytomegalovirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2005.01.004