(Q51506098)

6 April 2018

title

Interferon-γ plays a role in bone formation in vivo and rescues osteoporosis in ovariectomized mice. (English)

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Jake E. Barralet

11

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author name string

Dao Chao Huang

2

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Natalie Dion

3

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Michael Macoritto

4

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Daniel Rivas

5

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Wei Li

6

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Xian Fang Yang

7

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Jiarong Li

8

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Jing Lian

9

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Faleh Tamim Marino

10

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Viorica Lascau

12

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Claire Deschênes

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Louis-Georges Ste-Marie

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Richard Kremer

15

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publication date

1 July 2011

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Journal of Bone and Mineral Research

published in

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volume

26

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issue

7

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page(s)

1472-1483

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Osteoimmunology: crosstalk between the immune and bone systems

cites work

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Osteoimmunology: interactions of the bone and immune system

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Interplay between interferon and other cytokine systems in bone metabolism

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Interferon-gamma targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases.

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IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation

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Three-dimensional microimaging (MRmicroI and microCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis

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Understanding the mechanisms of senile osteoporosis: new facts for a major geriatric syndrome

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Immune defence in mice lacking type I and/or type II interferon receptors

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Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice

21 January 2018

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Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity

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Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.

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Inducible nitric oxide synthase mediates bone loss in ovariectomized mice

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Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.

21 January 2018

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Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized mice

21 January 2018

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Mathematical model of paracrine interactions between osteoclasts and osteoblasts predicts anabolic action of parathyroid hormone on bone.

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Hormone replacement therapy reverses the decrease in natural killer cytotoxicity but does not reverse the decreases in the T-cell subpopulation or interferon-gamma production in postmenopausal women

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T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

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21 January 2018

Identifiers

DOI

10.1002/JBMR.350

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6 April 2018

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