(Q51597433)

English

Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4′-hydroxylation*

scientific article published on August 1, 1995

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4′-hydroxylation* (English)

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10.1016/0009-9236(95)90193-0

https://api.crossref.org/works/10.1016/0009-9236(95)90193-0

15 July 2024

Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

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aryl hydrocarbon hydroxylases

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15 July 2024

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T. Ishizaki

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

K. Chiba

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

K. Manabe

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

E. Koyama

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

M. Hayashi

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

S. Yasuda

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

Y. Horai

7

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15 July 2024

Y. Tomono

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

C. Yamato

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

T. Toyoki

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7648765

15 July 2024

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publication date

1 August 1995

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7 April 2018

http://europepmc.org/abstract/MED/7648765

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

58

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

2

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

155-164

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Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

1 reference

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21 January 2018

Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

1 reference

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Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

1 reference

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Plasma diazepam and desmethyldiazepam concentrations during long-term diazepam therapy

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Desmethyldiazepam pharmacokinetics: studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam.

1 reference

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21 January 2018

American Journal of Physiology

1

243

G505

author name string

Fellenius E.

publication date

1982

1 reference

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15 July 2024

American Journal of Physiology

2

245

G64

author name string

Wallmark B.

publication date

1983

1 reference

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Omeprazole. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peptic ulcer disease and Zollinger-Ellison syndrome

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Clinical pharmacology of omeprazole

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Drug Metabolism and Disposition

6

17

69

author name string

Renberg L.

publication date

1989

1 reference

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The pharmacokinetics of omeprazole in humans--a study of single intravenous and oral doses

7

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Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.

8

1 reference

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Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects

10

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Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

14

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Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.

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Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

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Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

18

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Effect of omeprazole and cimetidine on plasma diazepam levels.

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Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

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Inhibitions of acid secretion by E3810 and omeprazole, and their reversal by glutathione.

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The potency of substituted benzimidazoles such as E3810, omeprazole, Ro 18-5364 to inhibit gastric H+, K(+)-ATPase is correlatedwith the rate of acid-activation of the inhibitor

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Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese

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Statistical moments in pharmacokinetics.

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Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

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Genetic polymorphism of S-mephenytoin hydroxylation

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Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations

30

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Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

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Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: a cocktail and extended phenotyping assessment trial

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Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

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443

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publication date

1985

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Delayed clearance of diazepam due to cimetidine.

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Clinical importance of the interaction of diazepam and cimetidine

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Comparison of the kinetic disposition and metabolism of E3810, a new proton pump inhibitor, and omeprazole in relation to S-mephenytoin 4′-hydroxylation status

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Molecular Pharmacology

49

37

767

author name string

Reilly P. E. B.

publication date

1990

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Identifiers

10.1016/0009-9236(95)90193-0

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 April 2018

http://europepmc.org/abstract/MED/7648765

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