(Q51617878)

English

Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.

scientific article published on 26 June 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions. (English)

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

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metabolic plasticity

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Kathrin Renner

1

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Anna-Lena Geiselhöringer

2

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Matthias Fante

3

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Christina Bruss

4

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Stephanie Färber

5

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Gabriele Schönhammer

6

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Katrin Peter

7

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Katrin Singer

8

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Reinhard Andreesen

9

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Petra Hoffmann

10

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Peter Oefner

11

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Wolfgang Herr

12

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Marina Kreutz

13

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

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publication date

26 June 2015

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

European Journal of Immunology

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

45

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

9

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Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

2504-2516

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

Metabolism, migration and memory in cytotoxic T cells

1 reference

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21 January 2018

Fueling immunity: insights into metabolism and lymphocyte function

1 reference

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Metabolic switching and fuel choice during T-cell differentiation and memory development

1 reference

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Metabolic checkpoints in activated T cells

1 reference

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Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling

1 reference

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Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells

1 reference

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21 January 2018

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

1 reference

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

1 reference

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21 January 2018

Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation

1 reference

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21 January 2018

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

1 reference

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21 January 2018

Posttranscriptional control of T cell effector function by aerobic glycolysis

1 reference

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21 January 2018

Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Inhibition of T cell-mediated cytolysis by 2-deoxy-D-glucose: dissociation of the inhibitory effect from glycoprotein synthesis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

The CD28 signaling pathway regulates glucose metabolism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Normal and cancer cell metabolism: lymphocytes and lymphoma.

1 reference

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21 January 2018

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

1 reference

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21 January 2018

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

1 reference

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21 January 2018

Effects of hypoxia and/or lack of glucose on cellular energy metabolism and cytokine production in stimulated human CD4+ T lymphocytes

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21 January 2018

Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease

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Bioenergetics of immune cells to assess rheumatic disease activity and efficacy of glucocorticoid treatment

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21 January 2018

Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis

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21 January 2018

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

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21 January 2018

Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis

1 reference

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21 January 2018

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

1 reference

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21 January 2018

Monocarboxylate transporter MCT1 is a target for immunosuppression

1 reference

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21 January 2018

Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

21 January 2018

Genetic disruption of lactate/H+ symporters (MCTs) and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin.

1 reference

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21 January 2018

Metabolic effects of 2-deoxy-D-glucose in isolated fat cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of glutamine on Th1 and Th2 cytokine responses of human peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545473

7 January 2021

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Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

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7 January 2021

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Identifiers

10.1002/EJI.201545473

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 April 2018

http://europepmc.org/abstract/MED/26114249

ResearchGate publication ID

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