(Q51695921)

English

The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse.

scientific article published on 18 May 2010

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse. (English)

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

type-1 diabetes

0 references

0 references

mathematical model

1 reference

based on heuristic

inferred from title

author name string

L Shoda

1

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

H Kreuwel

2

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

K Gadkar

3

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

Y Zheng

4

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

C Whiting

5

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

M Atkinson

6

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

J Bluestone

7

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

D Mathis

8

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

D Young

9

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

S Ramanujan

10

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

publication date

18 May 2010

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

161

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

2

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

250-267

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Cytokine dysregulation induced by apoptotic cells is a shared characteristic of macrophages from nonobese diabetic and systemic lupus erythematosus-prone mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Increased nonobese diabetic Th1:Th2 (IFN-gamma:IL-4) ratio is CD4+ T cell intrinsic and independent of APC genetic background

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Either IL-2 or IL-12 is sufficient to direct Th1 differentiation by nonobese diabetic T cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Helper requirements for generation of effector CTL to islet beta cell antigens

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2249.2010.04166.X

21 January 2018

Universally sloppy parameter sensitivities in systems biology models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Mechanisms mediating anti-CD3 antibody efficacy: insights from a mathematical model of type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

A comprehensive review of interventions in the NOD mouse and implications for translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

The NOD mouse: a model of immune dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Quantifying macrophage defects in type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Genetic background determines the size and structure of the endocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Guidelines for computer modeling of diabetes and its complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

'Educated' dendritic cells act as messengers from memory to naive T helper cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Transplacental exposure to bafilomycin disrupts pancreatic islet organogenesis and accelerates diabetes onset in NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Increased NF-kappa B activity in B cells and bone marrow-derived dendritic cells from NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Broadly impaired NK cell function in non-obese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Kinetic evolution of a diabetogenic CD8+ T cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

The Role of CD28 and CTLA4 in the Function and Homeostasis of CD4 + CD25 + Regulatory T Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Archimedes: a trial-validated model of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Tolerance mechanisms in murine autoimmune diabetes induced by anti-ICAM-1/LFA-1 mAb and anti-CD8 mAb.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Impairment of NK cell function by NKG2D modulation in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

B cells regulate autoimmunity by provision of IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Clearance of apoptotic beta-cells is reduced in neonatal autoimmune diabetes-prone rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

A model of beta-cell mass, insulin, and glucose kinetics: pathways to diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Class I-restricted presentation of exogenous antigen acquired by Fcgamma receptor-mediated endocytosis is regulated in dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

CD40-independent pathways of T cell help for priming of CD8(+) cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Onset of type 1 diabetes: a dynamical instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

NOD mice have a generalized defect in their response to transplantation tolerance induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

The APC1 concept of type I diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Peripheral selection of T cell repertoires: the role of continuous thymus output

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Glucagon-like-peptide-1 (7-36) amide improves glucose sensitivity in beta-cells of NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Life span of naive and memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Antigen-driven differentiation of naive Ig-transgenic B cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

CD28-mediated costimulation is necessary for optimal proliferation of murine NK cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Quantitative estimation of insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

29 September 2018

Triggering of murine NK cells by CD40 and CD86 (B7-2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909407

2 November 2018

Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orchestration of glucose homeostasis: from a small acorn to the California oak

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and Functional Characteristics of BM-Derived DC from NOD and Non-Diabetes-Prone Strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex steroids influence pancreatic islet hypertrophy and subsequent autoimmune infiltration in nonobese diabetic (NOD) and NODscid mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of homing and adhesion molecules in infiltrated islets of Langerhans and salivary glands of nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Course of pancreatic beta cell destruction in prediabetic NOD mice: a histomorphometric evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T cell subsets prior to and following diabetes in the NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of interleukin-1 alpha, interleukin-1 beta and interferon-gamma-inducing factor on the production of interferon-gamma by natural killer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of IL-4 prevents autoimmune diabetes but enhances pancreatic insulitis in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of pancreatic macrophages preceding and during early insulitis in young NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of Phagocytic Activity in Human Monocyte-Derived Dendritic Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-selectin is not required for T cell-mediated autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell compartments of prediabetic NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced incidence of insulitis in NOD mice following anti-CD3 injection: requirement for neonatal injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remission of established disease in diabetic NOD mice induced by anti-CD3 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic beta-cell destruction in non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20491795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.2010.04166.X

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

0 references

1 reference

Europe PubMed Central

9 April 2018

http://europepmc.org/abstract/MED/20491795

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q51695921&oldid=1784107047"