(Q51706814)

10 April 2018

title

Exploring QSARs for 5-lipoxygenase (5-LO) inhibitory activity of 2-substituted 5-hydroxyindole-3-carboxylates by CoMFA and CoMSIA. (English)

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author name string

Junxia Zheng

1

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Gaokeng Xiao

2

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Jialiang Guo

3

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Yang Zheng

4

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Hao Gao

5

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Suqing Zhao

6

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Kun Zhang

7

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Pinghua Sun

8

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publication date

13 June 2011

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Chemical Biology and Drug Design

published in

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volume

78

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issue

2

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page(s)

314-321

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5-Lipoxygenase: Cellular Biology and Molecular Pharmacology

cites work

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https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Prostaglandins and leukotrienes: advances in eicosanoid biology

21 January 2018

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Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Design and synthesis of novel 2-amino-5-hydroxyindole derivatives that inhibit human 5-lipoxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Structural optimization and biological evaluation of 2-substituted 5-hydroxyindole-3-carboxylates as potent inhibitors of human 5-lipoxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Cross-validated R2-guided region selection for comparative molecular field analysis: a simple method to achieve consistent results

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

Comparative molecular similarity index analysis (CoMSIA) to study hydrogen-bonding properties and to score combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2011.01146.X

10.1111/J.1747-0285.2011.01146.X

21 January 2018

Identifiers

DOI

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10 April 2018

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10 April 2018