(Q51726197)

10 April 2018

title

Comparison between recombinant P450s and human liver microsomes in the determination of cytochrome P450 Michaelis-Menten constants. (English)

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10 April 2018

author name string

K Youdim

series ordinal

1

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10 April 2018

R Dodia

series ordinal

2

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10 April 2018

language of work or name

English

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publication date

1 April 2010

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10 April 2018

published in

Xenobiotica

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10 April 2018

volume

40

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10 April 2018

issue

4

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10 April 2018

page(s)

235-244

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10 April 2018

Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.

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The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.

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Identifiers

DOI

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10 April 2018

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10 April 2018