(Q51737822)

English

Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma.

scientific article published on 27 February 2018

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

author name string

Hengyu Zhou

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Ying Cai

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Dina Liu

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Menghui Li

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Yu Sha

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Wenlu Zhang

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Jianping Gong

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Ailong Huang

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

publication date

27 February 2018

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Cell Proliferation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

51

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

e12447

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21 is a universal inhibitor of cyclin kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collaborative spirit of histone deacetylases in regulating chromatin structure and gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary liver cancer: worldwide incidence and trends

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sorafenib in advanced hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of histone deacetylases 1, 2, 3, and 7: HDAC2 is an independent predictor of survival in HCC

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent progress in understanding, diagnosing, and treating hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis and suppression of angiogenesis of hepatocellular carcinoma by HS-159, a novel phosphatidylinositol 3-kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC2 provides a critical support to malignant progression of hepatocellular carcinoma through feedback control of mTORC1 and AKT.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics, 2012

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone Deacetylase (HDAC) Inhibitors: Current Evidence for Therapeutic Activities in Pancreatic Cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in targeted therapies for hepatocellular carcinoma in the genomic era.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocellular carcinoma: epidemiology and risk factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29484736

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/CPR.12447

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29484736%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q51737822&oldid=1478193613"