(Q51747259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

13

1 reference

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18 March 2020

Manish Thakur

21

1 reference

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18 March 2020

author name string

Aimo Kannt

1

1 reference

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18 March 2020

Sridharan Rajagopal

2

1 reference

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18 March 2020

Sanjay Venkatachalapathi Kadnur

3

1 reference

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18 March 2020

Juluri Suresh

4

1 reference

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18 March 2020

Ravi Kanth Bhamidipati

5

1 reference

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18 March 2020

Srinivasan Swaminathan

6

1 reference

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18 March 2020

Mahanandeesha Siddappa Hallur

7

1 reference

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18 March 2020

Rajendra Kristam

8

1 reference

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18 March 2020

Ralf Elvert

9

1 reference

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18 March 2020

Jörg Czech

10

1 reference

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18 March 2020

Anja Pfenninger

11

1 reference

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18 March 2020

Christine Rudolph

12

1 reference

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18 March 2020

Devaraj Venkatapura Chandrasekar

14

1 reference

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18 March 2020

Vishal Subhash Mane

15

1 reference

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18 March 2020

Swarnakumari Birudukota

16

1 reference

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18 March 2020

Shama Shaik

17

1 reference

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18 March 2020

Bharat Ravindra Zope

18

1 reference

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18 March 2020

Raghunadha Reddy Burri

19

1 reference

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18 March 2020

Niranjan Naranapura Anand

20

1 reference

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18 March 2020

Manvi Singh

22

1 reference

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18 March 2020

Reejuana Parveen

23

1 reference

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18 March 2020

Saravanan Kandan

24

1 reference

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18 March 2020

Ramesh Mullangi

25

1 reference

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18 March 2020

Takeshi Yura

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Ramachandraiah Gosu

27

1 reference

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18 March 2020

Sven Ruf

28

1 reference

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18 March 2020

Saravanakumar Dhakshinamoorthy

29

1 reference

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18 March 2020

language of work or name

English

0 references

publication date

26 February 2018

1 reference

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18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

3660

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

18 March 2020

copyright license

start time

26 February 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Potential involvement of nicotinamide N-methyltransferase in the pathogenesis of metabolic syndrome

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Remodeling of hepatic metabolism and hyperaminoacidemia in mice deficient in proglucagon-derived peptides

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Reactive oxygen species have a causal role in multiple forms of insulin resistance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Coot: model-building tools for molecular graphics

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Refinement of macromolecular structures by the maximum-likelihood method

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

The CCP4 suite: programs for protein crystallography

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization

22 May 2018

1 reference

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Fluorometric assay of rat tissue N-methyltransferases with nicotinamide and four isomeric methylnicotinamides

22 May 2018

1 reference

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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Body weight predicts Nicotinamide N-Methyltransferase activity in mouse fat.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/db mice with degenerative diabetes.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Interferon-gamma elevates nicotinamide N-methyltransferase activity and nicotinamide level in human glioma cells

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Automated ligand placement and refinement with a combined force field and shape potential.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5826917

Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors.

30 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-018-22081-7

inferred from DOI database lookup

7 January 2021

based on heuristic

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-018-22081-7

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41598-018-22081-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

release_b7livwb6afdl5jzzayahvf7f4q

18 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/b7livwb6afdl5jzzayahvf7f4q

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29483571%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference