(Q51758133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Challenges in the conduct of disease-modifying trials in AD: practical experience from a phase 2 trial of Tau-aggregation inhibitor therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

main subject

phase II clinical trial

0 references

author

Roger T Staff

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

C Wischik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

publication date

1 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Nutrition, Health and Aging

24 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

367-369

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19300883%20AND%20SRC:MED&resulttype=core&format=json

Serial brain MRI at 3-6 month intervals as a surrogate marker for Alzheimer's disease

24 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

Independent accumulations of tau and amyloid beta-protein in the human entorhinal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

SPECT perfusion imaging in the diagnosis of Alzheimer's disease: a clinical-pathologic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12603-009-0046-5

Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease.

21 January 2018

1 reference

12 December 2020

Commentary on "Challenges to demonstrating disease-modifying effects in Alzheimer's disease clinical trials"

1 reference

12 December 2020

Automated discrimination between very early Alzheimer disease and controls using an easy Z-score imaging system for multicenter brain perfusion single-photon emission tomography.

1 reference

12 December 2020

Regional cerebral blood flow assessed with 99mTc-ECD SPET as a marker of progression of mild cognitive impairment to Alzheimer's disease.

1 reference

12 December 2020

Differentiation of dementia with Lewy bodies from Alzheimer's disease using brain SPECT.

1 reference

12 December 2020

Heterogeneity of cerebral blood flow in frontotemporal lobar degeneration and Alzheimer's disease.

1 reference

12 December 2020

Relevance of functional neuroimaging in the progression of mild cognitive impairment

1 reference

12 December 2020

Longitudinal changes in cognitive function and regional cerebral function in Alzheimer's disease: a SPECT blood flow study.

1 reference

12 December 2020

Superiority of 3-dimensional stereotactic surface projection analysis over visual inspection in discrimination of patients with very early Alzheimer's disease from controls using brain perfusion SPECT.

1 reference

12 December 2020

Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

1 reference

12 December 2020

Differentiation of dementia with Lewy bodies from Alzheimer's disease using Mini-Mental State Examination and brain perfusion SPECT.

1 reference

12 December 2020

The extent of neurofibrillary pathology in perforant pathway neurons is the key determinant of dementia in the very old

1 reference

12 December 2020

Association of atrophy of the medial temporal lobe with reduced blood flow in the posterior parietotemporal cortex in patients with a clinical and pathological diagnosis of Alzheimer's disease

1 reference

12 December 2020

Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease.

1 reference

12 December 2020

The evaluation of disease modifying therapies in Alzheimer's disease: a regulatory viewpoint

1 reference

12 December 2020

Cerebral perfusion correlates of conversion to Alzheimer's disease in amnestic mild cognitive impairment.

1 reference

12 December 2020

Challenges to demonstrating disease-modifying effects in Alzheimer's disease clinical trials.

1 reference

12 December 2020