(Q51760055)

English

Safety, pharmacokinetics and pharmocodynamics of recombinant human porphobilinogen deaminase in healthy subjects and asymptomatic carriers of the acute intermittent porphyria gene who have increased porphyrin precursor excretion.

scientific article published in January 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Safety, pharmacokinetics and pharmocodynamics of recombinant human porphobilinogen deaminase in healthy subjects and asymptomatic carriers of the acute intermittent porphyria gene who have increased porphyrin precursor excretion. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

acute intermittent porphyria

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Eliane Sardh

1

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Lillan Rejkjaer

2

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Dan E H Andersson

3

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Pauline Harper

4

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

publication date

1 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

46

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

4

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

335-349

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

https://scigraph.springernature.com/pub.10.2165/00003088-200746040-00006

0 references

Urinary porphyrin excretion in normal children and adults

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200746040-00006

21 January 2018

Urine and faecal porphyrin profiles by reversed-phase high-performance liquid chromatography in the porphyrias

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variations in porphobilinogen and 5-aminolevulinic acid concentrations in plasma and urine from asymptomatic carriers of the acute intermittent porphyria gene with increased porphyrin precursor excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenoviral-mediated expression of porphobilinogen deaminase in liver restores the metabolic defect in a mouse model of acute intermittent porphyria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porphyrins, porphyrin metabolism and porphyrias. II. Diagnosis and monitoring in the acute porphyrias

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme in the treatment of porphyrias and hematological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme biosynthesis in intermittent acute prophyria: decreased hepatic conversion of porphobilinogen to porphyrins and increased delta aminolevulinic acid synthetase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porphyrins, porphyrin metabolism and porphyrias. I. Update

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary delta-aminolevulinic acid (ALA) levels in lead poisoning. I. A modified method for the rapid determination of urinary delta-aminolevulinic acid using disposable ion-exchange chromatography columns

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of the porphyrias

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute intermittent porphyria in Sweden. Molecular, functional and clinical consequences of some new mutations found in the porphobilinogen deaminase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human porphobilinogen deaminase mutations in the investigation of the mechanism of dipyrromethane cofactor assembly and tetrapyrrole formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and biochemical characteristics and genotype-phenotype correlation in 143 Finnish and Russian patients with acute intermittent porphyria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical characterization of porphobilinogen deaminase-deficient mice during phenobarbital induction of heme synthesis and the effect of enzyme replacement

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme synthesis in chronic renal failure: the effects of hemodialysis, peritoneal dialysis and erythropoietin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17375984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200746040-00006

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

Dimensions Publication ID

0 references

release_wic2hkcy7nhufnt4sjffjgpsze

1 reference

https://api.fatcat.wiki/v0/release/wic2hkcy7nhufnt4sjffjgpsze

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/17375984

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