(Q51766886)

11 April 2018

title

Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans. (English)

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author

Vladimir Aseyev

5

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Heikki Tenhu

6

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author name string

Martina Hanzlíková

1

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Marika Ruponen

2

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Emilia Galli

3

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Atso Raasmaja

4

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Arto Urtti

7

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Marjo Yliperttula

8

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publication date

1 July 2011

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11 April 2018

published in

Journal of Gene Medicine

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volume

13

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issue

7-8

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page(s)

402-409

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Non-viral is superior to viral gene delivery.

cites work

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Extracellular and intracellular barriers in non-viral gene delivery

21 January 2018

1 reference

Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes

21 January 2018

1 reference

Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes.

21 January 2018

1 reference

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

21 January 2018

1 reference

Polyethylenimine-mediated gene delivery: a mechanistic study

21 January 2018

1 reference

Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis

21 January 2018

1 reference

Surface-Mediated Delivery of DNA: Cationic Polymers Take Charge

21 January 2018

1 reference

Proteoglycans: from structural compounds to signaling molecules

21 January 2018

1 reference

Evidence for the role of proteoglycans in cation-mediated gene transfer

21 January 2018

1 reference

Heparan sulfate proteoglycan as a plasma membrane carrier

21 January 2018

1 reference

Heparan sulphate proteoglycans and viral vectors : ally or foe?

21 January 2018

1 reference

Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer

21 January 2018

1 reference

Low molecular weight hyaluronan shielding of DNA/PEI polyplexes facilitates CD44 receptor mediated uptake in human corneal epithelial cells

21 January 2018

1 reference

The transport of nanosized gene carriers unraveled by live-cell imaging

21 January 2018

1 reference

A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin.

21 January 2018

1 reference

Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery

21 January 2018

1 reference

Monitoring of the formation and dissociation of polyethylenimine/DNA complexes by two photon fluorescence correlation spectroscopy

21 January 2018

1 reference

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

21 January 2018

1 reference

Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

21 January 2018

1 reference

A combinatorial polymer library approach yields insight into nonviral gene delivery

21 January 2018

1 reference

Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies

21 January 2018

1 reference

Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

21 January 2018

1 reference

Complexation of DNA with poly(methacryl oxyethyl trimethylammonium chloride) and Its poly(oxyethylene) grafted analogue

21 January 2018

1 reference

A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

21 January 2018

1 reference

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection

21 January 2018

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Poly(ethylenimine)-mediated gene delivery affects endothelial cell function and viability

21 January 2018

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Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

21 January 2018

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Role of polyplex intermediate species on gene transfer efficiency: polyethylenimine-DNA complexes and time-resolved fluorescence spectroscopy

21 January 2018

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Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JGM.1587

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11 April 2018

PubMed ID

21721076

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11 April 2018