(Q51767782)

English

Deletion of thyrotropin receptor residue Asp403 in a hyperfunctioning thyroid nodule provides insight into the role of the ectodomain in ligand-induced receptor activation.

scientific article published on 19 May 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

Deletion of thyrotropin receptor residue Asp403 in a hyperfunctioning thyroid nodule provides insight into the role of the ectodomain in ligand-induced receptor activation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

1 reference

based on heuristic

inferred from title

author name string

E Nishihara

1

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

C-R Chen

2

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

Y Mizutori-Sasai

3

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

M Ito

4

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

S Kubota

5

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

N Amino

6

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

A Miyauchi

7

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

B Rapoport

8

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

publication date

19 May 2011

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

Journal of Endocrinological Investigation

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

35

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

1

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

49-53

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

https://scigraph.springernature.com/pub.10.3275/7738

0 references

Detection of thyroid-stimulating hormone receptor and Gsalpha mutations: in 75 toxic thyroid nodules by denaturing gradient gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin and homologous glycoprotein hormone receptors: structural and functional aspects of extracellular signaling mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar prevalence of somatic TSH receptor and Gsalpha mutations in toxic thyroid nodules in geographical regions with different iodine supply in Turkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular dissection of the glycoprotein hormone receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular insights into TSH receptor abnormality and thyroid disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sporadic congenital hyperthyroidism due to a germline mutation in the thyrotropin receptor gene (Leu 512 Gln) in a Japanese patient.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin receptor gene mutations and TSH resistance: variable expressivity in the heterozygotes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin receptor mutations and thyroid hyperfunctioning adenomas ten years after their first discovery: unresolved questions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel thyrotropin receptor germline mutation (Asp617Tyr) causing hereditary hyperthyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic mutations in the thyrotropin receptor gene and not in the Gs alpha protein gene in 31 toxic thyroid nodules

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of ectodomain cysteine boxes 2 and 3 for the activation mechanism of the thyroid-stimulating hormone receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclinical nonautoimmune hyperthyroidism in a family segregates with a thyrotropin receptor mutation with weakly increased constitutive activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of TSH receptor and Gsalpha mutations in 45 autonomously functioning thyroid nodules in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281-->isoleucine) in the extracellular domain of the thyrotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/21597314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21597314

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