(Q51778003)

12 April 2018

title

Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f]quinoline. (English)

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12 April 2018

author name string

Yasuki Kitamura

1

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12 April 2018

Takashi Umemura

2

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12 April 2018

Keita Kanki

3

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12 April 2018

Yukio Kodama

4

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12 April 2018

Sachiko Kitamoto

5

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12 April 2018

Koichi Saito

6

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12 April 2018

Ken Itoh

7

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12 April 2018

Masayuki Yamamoto

8

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12 April 2018

Toshiaki Masegi

9

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12 April 2018

Akiyoshi Nishikawa

10

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12 April 2018

Masao Hirose

11

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12 April 2018

publication date

1 January 2007

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12 April 2018

published in

Cancer Science

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12 April 2018

volume

98

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12 April 2018

issue

1

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12 April 2018

page(s)

19-24

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12 April 2018

Overview of carcinogenic heterocyclic amines

cites work

1 reference

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Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis: results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine

21 January 2018

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DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

21 January 2018

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Evidence of direct generation of oxygen free radicals from heterocyclic amines by NADPH/cytochrome P-450 reductase in vitro

21 January 2018

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Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine

21 January 2018

1 reference

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

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Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response

21 January 2018

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Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism

21 January 2018

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Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

21 January 2018

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Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds

21 January 2018

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UDP-Glucuronosyltransferases

21 January 2018

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

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Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis

21 January 2018

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A crucial role of Nrf2 in in vivo defense against oxidative damage by an environmental pollutant, pentachlorophenol

21 January 2018

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Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

21 January 2018

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

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Chemistry-based studies on oxidative DNA damage: formation, repair, and mutagenesis

21 January 2018

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DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

21 January 2018

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Determination of malonaldehyde precursor in tissues by thiobarbituric acid test

21 January 2018

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Contrasting effects of acute and chronic dietary exposure to 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) on xenobiotic metabolising enzymes in the male Fischer 344 rat: implications for chemoprevention studies

21 January 2018

1 reference

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10.1111/J.1349-7006.2006.00352.X

21 January 2018

Identifiers

DOI

1 reference

12 April 2018

PubMed ID

17083568

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12 April 2018