(Q51810023)

12 April 2018

title

Importin-beta mediates Cdc7 nuclear import by binding to the kinase insert II domain, which can be antagonized by importin-alpha. (English)

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12 April 2018

author name string

Byung Ju Kim

series ordinal

1

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12 April 2018

Hoyun Lee

series ordinal

2

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12 April 2018

language of work or name

English

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publication date

21 February 2006

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12 April 2018

Journal of Biological Chemistry

published in

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12 April 2018

volume

281

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12 April 2018

issue

17

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12 April 2018

page(s)

12041-12049

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12 April 2018

The Cdc7 protein kinase is required for origin firing during S phase

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CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication

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Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

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Cdc7 protein kinase for DNA metabolism comes of age.

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Cdc7 kinase complex: a key regulator in the initiation of DNA replication

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Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7‐ASK kinase complex

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Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway

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Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

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Growth regulation of the expression of mouse cDNA and gene encoding a serine/threonine kinase related to Saccharomyces cerevisiae CDC7 essential for G1/S transition. Structure, chromosomal localization, and expression of mouse gene for s. cerevisiae

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Karyopherins: from nuclear-transport mediators to nuclear-function regulators

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Importin alpha transports CaMKIV to the nucleus without utilizing importin beta

21 January 2018

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Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.

21 January 2018

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Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip

21 January 2018

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The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals

21 January 2018

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Importin beta mediates nuclear translocation of Smad 3

21 January 2018

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Zinc finger domain of Snail functions as a nuclear localization signal for importin beta-mediated nuclear import pathway.

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Dynamics of DNA replication factories in living cells

21 January 2018

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Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

21 January 2018

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Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

21 January 2018

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Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

21 January 2018

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RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

21 January 2018

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Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells. Its protein kinase activity is regulated by Rad53p

21 January 2018

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Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

21 January 2018

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Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1

21 January 2018

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The structure of importin-beta bound to SREBP-2: nuclear import of a transcription factor

21 January 2018

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Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

21 January 2018

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Importin α: a multipurpose nuclear-transport receptor

21 January 2018

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A p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells

21 January 2018

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Radiation effects on DNA synthesis in a defined chromosomal replicon

21 January 2018

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Cellular stresses induce the nuclear accumulation of importin alpha and cause a conventional nuclear import block

21 January 2018

1 reference

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Nuclear Import of Creb and AP-1 Transcription Factors Requires Importin-β1 and Ran but Is Independent of Importin-α

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512630200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512630200

1 reference

12 April 2018

PubMed ID

16492669

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12 April 2018