(Q51836387)

13 April 2018

title

Mitochondrial D-loop mutation is a common event in colorectal cancers with p53 mutations. (English)

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13 April 2018

author name string

Shih-Ching Chang

1

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13 April 2018

Pei-Ching Lin

2

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13 April 2018

Shung-Haur Yang

3

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13 April 2018

Huann-Sheng Wang

4

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13 April 2018

Wen-Yih Liang

5

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13 April 2018

Jen-Kou Lin

6

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13 April 2018

publication date

7 February 2009

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13 April 2018

International Journal of Colorectal Disease

published in

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13 April 2018

volume

24

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13 April 2018

issue

6

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13 April 2018

page(s)

623-628

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13 April 2018

https://scigraph.springernature.com/pub.10.1007/s00384-009-0663-9

exact match

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cites work

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Identification of a putative p53 binding sequence within the human mitochondrial genome

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The p53 tumour suppressor gene

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The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells.

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Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999.

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High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations.

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Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

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Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

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Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma.

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Live or let die: the cell's response to p53

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Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

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p53 has a direct apoptogenic role at the mitochondria

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12 December 2020

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Somatic mutations of the mitochondrial genome in human colorectal tumours

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Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

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Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability

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Mitochondrial DNA alteration in gastric cancer

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Molecular biology of colorectal cancer

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In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

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p53 function and dysfunction

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p53 and metabolism: Inside the TIGAR.

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12 December 2020

Maintenance of mitochondrial DNA integrity: repair and degradation

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Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome.

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Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours

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p53 regulates mitochondrial respiration

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Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

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Clinical value of mitochondrial mutations in colorectal cancer.

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12 December 2020

10.1007/S00384-009-0663-9

Identifiers

DOI

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13 April 2018

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13 April 2018